摘要
目的探讨肾脏病患者真菌感染发病率、临床表现特点及预后等。方法前瞻性观察了我科近３年半收治的肾脏病患者中真菌感染的情况，并对真菌感染者予抗真菌治疗。结果１３４３例各类肾脏病患者中并发真菌感染者５０例（占３．７％），医院感染３９例，院外感染１１例，其中多部位感染者１６例。易感因素为老年患者，透析患者、难治性肾病综合征或病理类型难治者，长期应用激素和免疫抑制剂。结论肾脏病患者并发真菌感染并不少见，医院感染占多数，肺部真菌感染预后差，关键在于及时发现与治疗。
OBJECTIVE To investigate the incidence, clinical manifestation and prognosis of fungus infection in hospitalized patients with renal disease was studied. METHOD The condition of fungus infection in hospitalized patients with renal diseases in our centre had been observed during from Jan. 1993 to Jul. 1997. The clinical data of them were analysed. The patients who had fungus infection accepted antifungal drugs. RESULT 50 cases of fungus infection were found among 1343 cases who had different renal diseases (the percentage was 3.7%). The percentage of nosocomial infection was 78% and out of hospital infection was 22%. Among those patients, 16 cases had fungus infection in different organs meanwhile. The factors predisposing to fungus infection included elderly, peritoneal dialysis, renal insufficiency, refractory nephrotic syndrome and pathologic type, steriod therapy immunosuppression and broad-spectrum antibiotic therapy. CONCLUSION The results suggust the fungus infection in patients with renal diseases is not uncommon, most cases are nosocomial infection. The prognosis of pneumonia caused by fungus is very poor. Early diagnosis and prompt medical therapy may be instituted, but the prevention is more important.
出处
《中华医院感染学杂志》
CAS
CSCD
1998年第3期129-131,共3页
Chinese Journal of Nosocomiology
关键词
肾脏病
真菌感染
医院感染
Renal disease Fungus infection Nosocomial infection
