摘要
目的:探讨慢性肾脏疾病非透析患者医院感染的临床特点、危险因素。方法:调查472例慢性肾脏疾病非透析患者,分析这些患者的医院感染情况。结果:慢性肾脏疾病非透析患者的医院感染率和感染例次率与同期总的医院感染率和感染例次率比较明显增加,差异有统计学意义(P<0.05)。感染部位以泌尿道及下呼吸道多见,其次为上呼吸道;肾功能、血清蛋白、住院时间、抗菌药物及激素应用与医院感染密切相关。结论:慢性肾脏疾病非透析患者医院感染率较高。肾功能不全、免疫功能低下、长期应用激素等是医院感染的重要危险因素。
Objective: To investigate the clinical features and nosocomial infection risk factors of patients with non-dialysis-dependent chronic kidney disease(CKD).Methods: The data concerning nosocomial infection in 472 case with non-dialysis-dependent CKD were collected and analyzed.Results: Compared with the total hospital infection rate and infection case rate in the same stage,the hospital infection rate and infection cases rate of patients with non-dialysis-dependent CKD significantly increased(P〈0.05),and the infection often located on the urinary tract and lower respiratory tract,followed by upper respiratory tract.The risk factors of nosocomial infection included renal function,serum protein,hospitalization time,the use of antibacterial drugs.Conclusion: The patients with non-dialysis-dependent CKD are more susceptible to hospital infection than other patients,and the renal dysfunction,immune dysfunction,long-term use of hormone are main risk factor for hospital infection.
出处
《华夏医学》
CAS
2012年第4期478-480,共3页
Acta Medicinae Sinica
关键词
慢性肾脏疾病
非透析患者
医院感染
chronic kidney disease
non-dialysis patient
nosocomial infection