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L-乳酸调控乳酸产生菌产物光学纯度的分析 被引量：1

Effects of cultivation conditions on the optical purity of L(+)-lactic acid
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摘要 发酵初期在米根霉菌发酵培养基中添加L-乳酸可以调控发酵产物乳酸的光学纯度。随着L-乳酸添加量的增加,所产L-乳酸的光学纯度随之增加,当L-乳酸的添加量≥1.5g/L时,D-乳酸不再产生。同时,L-乳酸的产量、生物量、糖转化率也随之降低。该调控方法对乳酸菌调控产L-乳酸光学纯度影响不大,对大肠杆菌发酵调控产D-乳酸光学纯度没有效果。 The effect of cultivation conditions on the optical purity of L（＋）-lactic acid produced by Rhizopus oryzae HZS6 was investigated.The isomeric composition of lactic acid was influenced by the supplementation of L（＋）-lactic acid to fermentation medium.L（＋）-isomer increased with the dosage,no D（-）-lactic acid was observed when the concentration of supplemented L（＋）-lactic acid in matrix was ≥1.5 g/L.However,the L（＋）-lactic acid yield,biomass and glucose conversion rate decreased with the dosage.With the same method,the supplementation of L（＋）-lactic to substrate had no influence on isomeric composition of lactic acid by Lactobacillus and Escherichia coli.
作者 孟武 李十中 封文涛 张晗星 王瑞明
机构地区 山东轻工业学院食品与生物工程学院 清华大学核能与新能源研究院
出处 《生物工程学报》 CAS CSCD 北大核心 2009年第11期1679-1683,共5页 Chinese Journal of Biotechnology
基金 "十一五"国家科技支撑计划(No.2006BAD07A00)资助~~
关键词 L-乳酸 D-乳酸 光学纯度 米根霉 乳酸菌 大肠杆菌 调控 L（＋）-lactic acid D（＋）-lactic acid optical purity Rhizopus oryzae Lactobacillus Escherichia coli regulation
分类号 R318.08 [医药卫生—生物医学工程]
  • 相关文献

参考文献10

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二级参考文献16

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共引文献23

同被引文献19

  • 1徐忠,汪群慧,姜兆华.L-乳酸的制备及其应用的研究进展[J].化学与粘合,2004,26(4):214-217. 被引量：19
  • 2曾炜,陈丰秋,詹晓力.乳酸的生产技术及其研究进展[J].化工进展,2006,25(7):744-749. 被引量：25
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生物工程学报
2009年 第11期

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