摘要
目的通过对蛇鳞草的小鼠灌胃急性毒性实验研究,指导其临床用药的安全性。方法通过预实验,判断测定LD50的可能性,并据此测定LD50或MTD。结果MTD结果表明小鼠口服蛇鳞草的最大耐受量相当于60 kg人临床日用量的646倍。结论蛇鳞草的急性毒性很小。
Objective To study the acute toxicity of Shelincao, so as to guide its clinical drug safety. Methods The possibility of determining LD50 was judged through pretest. The LD50 or maximum tolerance dose （MTD） was measured by intragastric administration of the Shelincao with the maximum concentration and the maximum amounts in mice. Results The MTD test showed that the MTD of mice was equal to 646 times of the normal human （60 kg）. Conclusion Shelincao has no acute toxicity.
出处
《今日药学》
CAS
2009年第11期21-22,共2页
Pharmacy Today
基金
中山市科技计划立项项目(编号:20071A036)
