摘要
目的研究吸烟对男性人群中肺癌的影响。方法收集经组织学或细胞学诊断明确患有肺癌的644例男性患者的临床资料，按吸烟与否分为吸烟组和非吸烟组，并进行回顾性分析。结果吸烟组鳞癌患者所占比例明显高于非吸烟组（40．08％vs 20．67％，P〈0．01），非吸烟组腺癌患者比例高于吸烟组（68．00％vs 44．53％，P〈0．01）。非吸烟组非小细胞肺癌晚期患者的比例高于吸烟组（P=0．016）。吸烟组咳嗽与咯血症状较非吸烟组明显（P值分别为0．032、0．008），非吸烟组无症状患者多于吸烟组（P=0．003）。结论吸烟男性肺癌患者中鳞癌比例较高，咳嗽和咯血症状明显；非吸烟男性肺癌患者以腺癌常见，临床表现不明显；非吸烟男性患者非小细胞肺癌晚期病例较吸烟男性患者多。
Objective To investigate the effect of smoking on male patients with lung cancer. Methods Clinical data of 644 male patients with lung cancer who were diagnosed by histology or cytology were collected and retrospectively analyzed. Patients were divided into smoking group and non-smoking group. Results There were more squamous cell carcinoma patients in smoking group （40.08%） than non-smoking group （20.67%, P 〈0.01）, but less adenocarcinoma patients in smoking group（44.53% ） than non-smoking group （68. 00%, P 〈0.01）. The patients with advanced stage of non-small cell lung cancer in non-smoking group were more than those in smoking group（ P =0. 038）. More patients in smoking group suffered from cough （ P =0.032） and hemoptysis （ P = 0. 008）. The asymptomatic patients in non-smoking group were more than those in smoking group （ P = 0. 003）. Conclusions In male smoking patients with lung cancer, the proportion of squamous cell carcinoma is high,and the symptom of cough and hemoptysis is obvious. In male non-smoking patients with lung cancer, adenoearcinoma is common, and clinical manifestation is not obvious. The patients with advanced stage of non-small cell lung cancer in non-smoking male patients are more than those in smoking male patients.
出处
《国际呼吸杂志》
2009年第22期1358-1361,共4页
International Journal of Respiration
基金
上海市重点学科建设项目（B112）
关键词
肺癌
男性
吸烟
Lung cancer
Male
Smoking
