摘要
目的探讨Wernicke脑病的临床、影像学特点。资料与方法回顾性分析4例Wernicke脑病患者的临床、影像学资料。结果4例均非酒精中毒患者,临床均有不同程度精神、意识障碍,发病前3例有不同程度的恶心、呕吐,眼肌麻痹2例,4例均行MRI头颅扫描,3例首诊阳性,1例首检漏诊,复查发现。MRI均表现为第三、四脑室及中脑导水管周围对称性的长T1、长T2异常信号。2例经维生素B1治疗明显好转,1例死亡。结论Wernicke脑病临床表现常不典型,MRI检查可为Wernicke脑病的早期诊断提供帮助,及早治疗、预后较好。
Objective To investigate the clinicaland imaging features of Wernicke encephalopathy （WE）. Materials and Methods The clinical and imaging data of 4 patients with WE were analyzed retrospectively. Results The clinical symptom presented various mental and conscious disturbance. Included initiatlly presented nausea and vomiting in 3 cases, ophthamoparalysis in 2 cases. MRI imagings showed symmetric hypointense on T1WI and hyperintense on T2WI in periventrical and periaqueductal parenchyma. 2 cases quickly responded to supplement Vit B1,1 case died. Conclusion The clinical manifestations of WE is atypical. MRI imaging is helpful for early diagnosis of WE. Thiamine supplement as early as possible is the key treatment.
出处
《临床放射学杂志》
CSCD
北大核心
2009年第11期1560-1562,共3页
Journal of Clinical Radiology
