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舒芬太尼用于晚期癌痛患者PCEA的临床研究

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摘要 ①目的观察舒芬太尼与甲磺酸罗哌卡因复合用于晚期癌痛患者硬膜外自控镇痛(PCEA)的疗效。②方法将120例晚期癌痛患者随机分为A组(舒芬太尼+甲磺酸罗哌卡因组)、B组(芬太尼+甲磺酸罗哌卡因组)、C组(吗啡+甲磺酸罗哌卡因组)。根据疼痛部位的神经支配节段行PCEA,观察镇痛用药后各时点的镇痛效果及相关不良反应。③结果镇痛用药8h内A组的VAS评分明显低于B、C组,B、C组间无明显差异。呼吸抑制副作用A组明显低于B、C组。其他恶心、呕吐、皮肤瘙痒等不良反应三组间无明显差异。④结论舒芬太尼合用小剂量甲磺酸罗哌卡因用于晚期癌痛患者PCEA疗效确切,不良反应发生率低。
出处 《华北煤炭医学院学报》 2009年第6期804-805,共2页 Journal of North China Coal Medical College
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