摘要
目的探讨卵巢支持-间质细胞瘤的临床表现、治疗及预后。方法回顾性分析10例支持-间质细胞瘤患者的临床及病理资料。结果10例患者中,7例表现为月经稀发或闭经,其中4例合并腹部肿块;2例出现阴道不规则流血;1例表现为腹痛。5例未生育患者,4例行患侧附件切除术,1例行患侧附件切除、对侧卵巢部分切除术。5例已生育患者,2例行全子宫+双侧附件切除术,2例行全子宫+双侧附件切除术+大网膜切除术,1例行全子宫+双侧附件切除术+大网膜切除术+阑尾切除术+盆腔淋巴结清扫术。10例患者中,除1例于术后第3年失访外,其余9例均健在,且无复发及转移。结论卵巢支持-间质细胞瘤治疗以手术为主。根据患者的年龄、生育要求、临床分期、分化程度以及肿瘤有无破裂来确定手术范围,总体预后远好于卵巢上皮性癌。
[ Objectives ] To investigate the chnical characteristics, management and prognosis of ovarian Setoli- Leydig cell tumor. [ Methods ] 10 patients with ovarian Setoli-Leydig cell tumor were retrospectively reviewed. [ Resuits] 7 cases presented with menstruation or amenorrhea, in which 4 cases combined with abdominal-pelvic masses. 2 cases presented with irregular vaginal bleeding. 1 case presented with abdominal pain. All patients were subjected to operation. 1 case lost and 9 cases survived with no recurrence or metastasis after follow-up so far. [ Conclusions ] Surgery is the best choice for ovarian Setoh-Leydig cell tumor. The scope of surgery is determined according to age, fertility requirement, clinical stage, tumor differentiation and whether or not breakdown of the tumor. The overall prognosis is far better than epithelial ovarian cancer.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2009年第19期2968-2971,共4页
China Journal of Modern Medicine
