摘要
同源异型盒基因编码控制多细胞真核生物发育的转录因子,参与调控细胞分化的命运,在生物的形态建成中发挥着重要作用。KNOX(KNOTTED1-like homeobox genes)家族是植物中的5个同源异型盒基因家族之一,几乎存在于所有的单子叶和双子叶植物中,被分为两类亚家族:I类KNOX亚家族(KNOXI)和II类KNOX亚家族(KNOXII),其中KNOXI主要在植物分生组织中表达,是分生组织发生与维持所必需的关键基因,调控与器官发生相关的细胞分化,最终影响侧生器官的形态建成。本文重点对KNOXI基因的表达模式、调控及在植物形态建成中的作用等进行阐述。
Homeobox genes encode an important class of transcription factors which play crucial roles in developmental regulation of multicellular eukaryotes. A large number of homeobox genes isolated from yeast, fungi, animals and plants have been studied extensively. KNOX genes, one of the five homeobox gene families in plant, almost exist in all monocot and dicot plants. According to sequence similarities and differences in expression patterns, KNOX genes can be divided into class-1 （KNOXⅠ） and class-2 （KNOX Ⅱ） subclasses. Class I KNOX genes, characteristically expressed in meristem, are essential for meristem initiation and maintenance by controlling cell specification and proper patterning of organ initiation. This review focuses on the expression patterns and regulation of class I KNOX genes and their functions in plant morphogenesis.
出处
《细胞生物学杂志》
CSCD
2009年第5期635-640,共6页
Chinese Journal of Cell Biology
基金
国家自然科学基金(No.G30370087)
甘肃省自然科学基金(No.ZX021-A25-047-N)资助项目~~
