摘要
目的探讨恩必普软胶囊对卒中后痴呆的发生以及认知功能和行为功能的影响。方法急性脑梗死178例,随机分为恩必普软胶囊治疗组和对照组,每组89例,发病3月检测各组痴呆发生、简易智能状态检测量表(Mini-mental state examination,MMSE)和日常生活能力评分(Activities of daily living scale,ADL)。结果恩必普软胶囊治疗组卒中后痴呆发病率(5/89)显著少于对照组(13/89),恩必普软胶囊治疗患者认知(25.3±2.79)和行为能力(57.1±13.3)好于对照组(24.20±4.43,52.4±17.7)。结论恩必普软胶囊可以减少卒中后痴呆的发生。
Objective To investigate the influence of butylphthalide on incidence of post stroke dementia （PSD）. Methods 178 patients with acute ischemic stroke were randomly divided into two groups, including treatment group treated with butylphthalide for 3 months and control group treated with routine therapy. MMSE Scale and ADL Scale were assessed. Results The incidence rate of PSD in treatment group was lower than that in control group. MMSE Scale and ADL Scale of treatment group were higher than that in control group. Conclusion Early treated with butylphthalide can reduce incidence of post stroke dementia.
出处
《西部医学》
2009年第11期1899-1900,1903,共3页
Medical Journal of West China
关键词
恩必普
卒中后痴呆
卒中
Butylphthalide
Post stroke dementia
Stroke
