摘要
应用根据Minami法加以改进而建立的微量快速SOD测定法.观察30例冠心病与11例可疑冠心病患者红细胞和血浆中SOD的含量及应用复方丹参注射液加低分子右旋糖酐静脉滴注后SOD含量的变化。结果表明:冠心病患者红细胞和血浆中的SOD含量明显降低,血浆SOD含量的变化能更敏感地反映心肌受损情况。静脉滴注复方丹参液加低分子右旋糖酐后,冠心病患者血中SOD含量明显增高,提示该疗法能减轻缺血/再灌注过程中产生的O^-_2对心肌的损伤。
The fluctuation of superoxide dismutase ( SOD) levels in erythrocyte and plasma on patients sufferring from coronary heart disease ( CHD) and the changes of SOD after infusion of injectio salvia miltiorrhizae composita plus low molecular dextran were observed. The results showed that SOD levels in erythrocyte and plasma of patients with CHD were lower than that of patients without sufficient evidences of myocardial ischemia. The extent of decrease, especially that in plasma, was correlated with the seriousness of the disease. The increased SOD levels in erythrocyte and plasma after infusion of injectio Salvia miltiorrhizae composita plus low moiecular dextran suggested that this therapy may reduce the ischemia/reperfusion injury as well as improve the oxygen supply of ischemic myocardium.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
1990年第2期83-85,共3页
Journal of Clinical Cardiology
