摘要
目的:探讨缺血性脑卒中辨证分型的客观依据。方法:本研究对120例缺血性脑卒中患者按中医辨证分型进行分组,观察各证型组病例的颈动脉粥样斑块的变化及血液流变学改变。结果:研究表明,风痰瘀阻和痰热腑实组的斑块检出率、斑块面积均明显大于气虚血瘀组和风痰火亢组,有显著性差异(P<0.05～0.01);颈部斑块性质方面,痰热腑实组和风痰瘀阻组与气虚血瘀组、风痰火亢组相比差异显著(P<0.05);风痰火亢组、痰热腑实组血液流变学较对照组及气虚血瘀组有显著差异(P<0.05～0.01)。结论:颈动脉粥样斑块的变化和血液流变学指标可为缺血性脑卒中辨证分型提供客观依据。
Objective： To study the relationship between syndrome differentiation of TCM and carotid artery athero- sclerotic plaques （ CAAP）, transcranial doppler （TCD） in cerebral infarction （CI） syndromes, which supplies objective index for microscosmic syndrome differentiation of TCM in CI. Methods ： 120 CI selected cases and classified into the 4 groups according to syndrome differentiation classified in TCM, and 20 cases of healthy pepole were selected as the normal control group（NCG）. The 4 different types of TCM of CI were compared with each other by TCD and ultrasound, then were compared with the control group, observing the change of indexex to study the relationship. Results ： Study shows that the Meridian- phlegm stagnancy group （MPS） and the visceral phlegm- heat accumulation group （VPHA） were was significandy higher than the qi - deficiency with blood stasis （ QDBS ） and the excess of wind - phlegm - fire syndrome （EWPFS） （ P 〈 0.05- 0.01 ）. The VPHA and WPS were significantly higher than QDBS and EWPFS （ P 〈 0.05 ）. EWPFS and VPHA comparied with the control group hemorheology and QDBS hemorheology were significantly different（ P 〈 0.05 - 0.01 ）. VPHA and MPS compared with QDBS and EWPFS were significantly different. Conclusion： The relation- ship between syndrome diferentiation of TCM and TCD, carotid ultrasound with CI is clear. The two examinations may ofer objective reference to syndrome diferentiation of TCM of CI.
出处
《中华中医药学刊》
CAS
2009年第11期2459-2462,共4页
Chinese Archives of Traditional Chinese Medicine
关键词
缺血性脑卒中
辨证分型
颈动脉粥样斑块
血液流变学
TCD
cerebral infarction
syndrome diferentiation of TCM
earotid artery atherosclerotic plaques
transcranial doppler
Hemorheology
