摘要
目的：建立碰撞池ICP-MS直接测定尿液中16个痕量有毒元素的准确分析方法。方法：采用0.1%HNO3＋200μg/L Au对尿液稀释5倍后直接用ICP-MS进行分析,并采用碰撞/反应池技术来消除质谱干扰。结果：方法的检出限为0.01-0.25μg/L,精密度优于3.3%,回收率为94.0%-104%,标准参考物质的分析结果令人满意。结论：可用ICP-MS直接测定尿液中的16个痕量金属元素,整个方法具有简单、快速和准确的特点。
Objective：To develop a accurate method for direct determination of sixteen trace elements in urine by collision cell inductively coupled plasma mass spectrometry.Methods：After dilution with 0.1%HNO3＋200 μg/L Au by a factor of 5,the urine was directly determined by inductively coupled plasma mass spectrometry using collision cell to eliminate mass spectroscopic interference.Results：The detections of limits were 0.01 0.25 μg/L,the RSD less than 3.3%,recoveries 94.0%-104% and the results of analyzing standard materiel were satisfactory.Conclusion：This method is simple,sensitive and accurate.It can be used for can direct determination of sixteen trace metal elements in urine.
出处
《中国卫生检验杂志》
CAS
2009年第11期2475-2477,共3页
Chinese Journal of Health Laboratory Technology
基金
广东省医学科研课题(A2008571)
广州市医学科研课题(2007-YB-122
2007-YB-123)
关键词
ICP-MS
直接测定
尿液
痕量元素
Inductively coupled plasma mass spectrometry
Direct determination
Urine
Trace elements
