摘要
本文选择22例择期手术病人,用加速度仪观察静脉普鲁卡因全麻对阿曲可林作用时效的影响。静滴普鲁卡因维持麻醉时使阿曲可林(0.5mg/kg)的起效时间和高峰时间略缩短,使高峰持续时间和肌松维持时间略延长,但均无统计学意义。然而,静脉普鲁卡因能使阿曲可林的恢复率延长77％。普鲁卡因协同阿曲可林的机制不清,有待进一步研究。
The interaction between intravenous procaine and atracurium was studied by means of accelograph in 22 adult patients (ASA Class I or II)undergoing elective abdominal surgery. After a bolus of atracurium in 0.5mg/kg,the onset course and duration time of atracurium were slightly shortened and prolonged respectively(P>0.05) by intravenous procaine infusion at a rate of 1mg/kg/min,However,the recovery time of atracurium was prolonged significantly(P<0.01). The results demonstrated that the relaxation action of natracurium can be potentiated by intravenous procaine.
出处
《临床麻醉学杂志》
CAS
CSCD
北大核心
1990年第4期225-227,共3页
Journal of Clinical Anesthesiology
