摘要
目的探讨性染色体异常与男性不育之间的关系。方法对在我院遗传咨询、生殖健康、育前检查门诊中,男性不育患者236例,作外周血淋巴细胞培养,染色体核型分析。结果发现性染色体异常核型36例,检出率为15.3%。其中数目异常核型20例,占55.6%,结构异常3例,占8.3%,多态性变异13例,占36.1%。结论性染色体异常是导致男性不育的重要原因。
Objective： To investigate the sex chromosome abnormalities and the relationship between male infertility. Methods： The genetic counseling at the hospital, reproductive health, fertility clinic before the examination, 236 cases of male infertility patients, for peripheral blood lymphocytes culture, karyotype analysis. Results ： The sex chromosome abnormalities found in 36 cases of nuclear - detection rate of 15.3 percent. In which the number of abnormal karyotypes in 20 cases, accounting for 55.6% , 3 cases of abnormal structure, accounti -ng for 8. 3% , 13 cases of variant polymorphisms, accounting for 36. 1 percent. Conclusions： The sex chromosome abnormality is a major cause of male infertility.
出处
《中国优生与遗传杂志》
2009年第10期58-59,共2页
Chinese Journal of Birth Health & Heredity
关键词
性染色体
男性不育
核型
Sex chromosome
Male infertility
Karyotype
