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HSP70在食蟹猴睾丸不同发育阶段的表达研究 被引量:1

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摘要 目的观察热休克蛋白70(HSP70)在食蟹猴睾丸发育成熟过程中的表达特征,探讨其在睾丸发育成熟中的作用。方法用Eli VisionTM免疫组织化学技术检测食蟹猴从新生猴期至成年猴期不同发育阶段睾丸HSP70的表达。结果30只食蟹猴睾丸均表达HSP70。在新生猴期、童猴前期、童猴后期的睾丸中,HSP70主要表达于精原细胞的胞质;在青春猴期,HSP70主要表达于精母细胞的胞质中,精原细胞只有少量表达;在成年猴期,HSP70主要表达于精母细胞和精子细胞的胞质中,精原细胞则无明显表达。各个发育阶段中,支持细胞和间质细胞未见明显HSP70表达。结论HSP70在食蟹猴睾丸不同发育阶段的表达差异,提示HSP70对睾丸的形态发育及精子发生起调节作用。
出处 《山东医药》 CAS 北大核心 2009年第40期32-33,共2页 Shandong Medical Journal
基金 广西"新世纪十百千人才工程"资助项目(2001208)
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