摘要
目的系统评价清开灵注射液用于脑血管疾病的临床疗效。方法采用RevMan5.0软件,对国内1994-2008年发表的运用清开灵注射液治疗脑血管疾病的临床对照试验进行Meta分析,对不同纳入标准的研究结果进行了敏感度分析。结果疗效评价共纳入38个临床对照试验研究,采用固定效应模型计算,清开灵注射液治疗脑血管疾病的效应值OR =3.26,95%置信区间为[2.71,3.92]。结论清开灵注射液对脑血管疾病的治疗与对照组相比,疗效可能优于对照组,但尚待高质量随机对照试验证实。
Objective To evaluate the efficacy of Qingkalling injection for cerebrovascular diseases by systematic review of clinical trials. Methods Meta-analysis was used to evaluate the efficacy of Qingkailing injection on cerebrovascular diseases from 38 articles on clinical trials published from 1994 to 2008 in Chinese journals with the software RevMan5.0. Sensitivity analysis was taken to analyze the results of trails with different inclusion criteria. Results 38 clinical control trails were included for efficacy analysis, a fixed effects model was chosen and the value of odds ratio （OR） was 3.26 with the 95% confidence interval from 2.71 to 3.92. Conclusions Qingkailing injection may have positive effect on cerebrovascular diseases, its efficacy need to be confirmed with high-quality randomized controlled trials.
出处
《中国中医药信息杂志》
CAS
CSCD
2009年第11期105-107,共3页
Chinese Journal of Information on Traditional Chinese Medicine
基金
国家科技支撑计划(2008BAI55804)
关键词
清开灵注射液
脑血管疾病
META分析
Qingkalling injection： cerebrovascular diseases： Meta-analysis
