摘要
目的：观察早产儿肺透明膜病（ＨＭＤ）临床特点与多器官损害的关系，胎儿宫内失血和宫内缺氧的临床特点、多器官损害和对预后的影响。方法：早产儿ＨＭＤ中宫内缺氧缺血组１０８例，出生后缺氧组４６例；死亡病例均经尸检确诊。ＨＭＤ均检测血气、心电图、多项生化指标，并摄胸腹部Ｘ线片。结果：１５４例ＨＭＤ中普通型１０２例，休克型５２例。多器官损害率：普通型６５６９％（６７／１０２），休克型９０３８％（４７／５２）。病死率：普通型４７０６％（４８／１０２），休克型９４２３％（４９／５２）。休克发生率分别为胎儿缺氧缺血组４６３０％（５０／１０８），出生后缺氧组４３５％（２／４６）。结论：胎儿宫内失血和宫内缺氧是导致早产儿ＨＭＤ并发休克、多器官损害最危险的病理因素，对预后影响极为严重，应引起高度重视。
Objective:To study the clinical features related to multiple organs injuries in hyaline membrane disease(HMD)of premature infants,and the influence of blood loss and anoxia of fetus on clinical features,multiple organs injuries and prognosis.Methods:108 cases with ischemia and anoxia of fetus,and 46 cases in group of anoxia of infants after birth in 154 cases of HMD were studied.All cases of death diagnosed by autopsies.All cases of HMD examined in blood gases,cardiographs,multiple biochemical index,and were checked by radiographs of chest and abdomen.Results:There were 102 cases in common type and 52 cases in shock type of HMD.The rate of multiple organs injuries were 65 69%(67/102)in commom type,and 90 38%(47/52)in shock type,respectively.The mortality were 47 06%(48/102)in common type and 94 23%(49/52)in shock type,respectively.The rate of shock was 46 30%(50/108)in group of ischemia and anoxia of fetus,and 4 35%(2/46)in group of anoxia of infants after birth,respectively.Conclusion:Blood loss and anoxia of fetus are the most dangerous pathological factors causing HMD of premature infants associated with shock and multiple organs injuries,which seriously affect the prognosis of HMD.Thus,it requires intensive attention and immediate observation. \ \
出处
《中国实用儿科杂志》
CSCD
北大核心
1998年第6期351-353,共3页
Chinese Journal of Practical Pediatrics
关键词
早产儿
肺透明膜病
多器官衰竭
预后
Infant premature\ Hyaline membrane disease\ Shock\ Multiple organs injuries
