摘要
目的研究肿瘤标志物CA242与CEA对结直肠癌的诊断作用。方法选择2006年1月～2008年12月本科住院患者,75例结直肠癌患者进行了CA242和CEA的检测。结果CA242与CEA较对照组明显升高,其中75例结直肠癌患者中CA242阳性70例,检测的灵敏度93.3%,特异度73.8%;CEA阳性60例,检测的灵敏度80%,无显著差别(P>0.05)。并且10例结直肠癌手术后3周接近正常,治疗观察2年,CA242无升高,临床无复发和转移征象。17例手术后3年也有不同程度降低,但仍然高于正常人,并且进行性升高,6～12月出现复发或其他部位转移。结论CA242与CEA可用于结直肠癌的诊断、术后随访、治疗疗效的检测有十分重要的意义,并且CA242监测结直肠癌复发或转移方面较CEA可靠,因此术后动态观察CA242是一项优于CEA的肿瘤标志物。
Objective Study on tumor markers CA242 and CEA for colorectal cancer diagnosis. Methods Select from January 2006 to December 2008 our patients, 75 cases of colorectal cancer patients with a CA242 and CEA detection. Results CA242 and CEA significantly higher than the control group, 75 cases of colorectal cancer in 70 cases of positive CA242, sensitivity 93.3%, specificity 73.8%; CEA positive in 60 cases, 80% sensitivity, the difference between poor （P〉0.05）. Conclusion CA242 and CEA can be used for the diagnosis of colorectal cancer, postoperative follow-up, ti-eatment effects are very important for detection and CA242 to monitor recurrence or metastasis of colorectal cancer than CEA and reliable, so the dynamic observation of patients is a better than CA242 CEA tumor marker.
出处
《当代医学》
2009年第31期50-51,共2页
Contemporary Medicine
