摘要
目的:探讨电针干预对多囊卵巢综合征(PCOS)患者在行体外受精-胚胎移植(IVF-ET)中的作用。方法:将接受IVF-ET助孕的96例PCOS患者随机分为观察组50例和对照组46例,两组均给予促性腺激素释放激素激动剂长方案,观察组加用电针干预,比较两组治疗疗效。结果:观察组IVF受精率(75.12%)、优质胚胎率(63.53%)明显高于对照组(64.72%、50.11%),促性腺激素(Gn)用量(29.15±3.85)单位,低于对照组(36.21±5.37)单位,且具有统计学意义(P<0.05)。OHSS发生率(10.00%)低于对照组(10.86%),种植率(18.60%)、临床妊娠率(37.77%)高于对照组(17.10%、31.70%),但没有统计学意义,Gn用药时间、获卵率、卵裂率、hCG注射日E2、P、LH水平没有显著差别。结论:对行IVF的PCOS患者给予电针干预具有良好的临床效果。
Objective：To explore the effect of electroacupuncture intervention on in vitro fertilization and embryo transfer（IVF-ET） of patients with polycystic ovarian syndrome（PCOS）.Methods：96 PCOS patients who accepted IVF-ET were divided into observation group（50 cases） and control group（46 cases） randomly.Two groups were given long program of gonadotropin releasing hormone agonist（GnRHa）,additionally,patients in observation group were treated by electroacupuncture,then therapeutic effects of two groups were compared.Results：The fertilization rate and high-quality embryo rate in observation group（75.12%,63.53%） were significantly higher than those in control group（64.72%,50.11%）,while the dosage of GnRHa in observation group（（29.15±3.85） U） was lower than that in control group（（36.21±5.37） U）（P〈0.05）.The incidence of ovarian hyperstimulation syndrome in observation group（10.00%） was lower than that in control group（18.60%）,while the implantation rate and clinical pregnancy rate in observation group（18.60%,37.77%） were higher than those in control group（17.10%,31.70%）,but there was no difference.There was no significant difference in duration of therapy,rate of oocytes per retrieval,cleavage rate and levels of estrogen,progestogen and luteinizing hormone on hCG day between two groups.Conclusion：Electroacupuncture is effective in IVF-ET of patients with PCOS.
出处
《中国妇幼保健》
CAS
北大核心
2009年第30期4262-4264,共3页
Maternal and Child Health Care of China
基金
山东省自然科学基金项目〔Y2007C131〕
关键词
电针
多囊卵巢综合征
IVF-ET
Electroacupuncture
Polycystic ovarian syndrome
In vitro fertilization and embryo transfer
