摘要
目的:观察更昔洛韦联合西咪替丁治疗轮状病毒肠炎的效果。方法:167例轮状病毒肠炎患儿随机分成更昔洛韦联合西咪替丁治疗组(A组)60例、病毒唑治疗组(B组)52例、对照组(C组)55例。三组病例均给予补液,维持水、电解质、酸碱平衡等综合治疗。结果:更昔洛韦联合西咪替丁治疗组(A组)、病毒唑治疗组(B组)、对照组(C组)的治疗总有效率分别为96.6%、82.7%、78.2%,其中A组显著高于B组、C组(P均<0.05)。结论:更昔洛韦联合西咪替丁治疗轮状病毒肠炎,效果佳且安全,两者有协同作用。
Objective：To observe the effect of ganciclovir and cimetidine therapy in infants with rotavirus enteritis. Methods ： One hundred and sixty-seven infants with rotavirus enteritis were randomly allocated to the group of ganciclovir ＋ cimetidine therapy （ Group A, n = 60 ）, virazole treatment（ Group B, n = 52 ） and control subjects （ Group C, n = 55 ）. In general,the three groups were given comprehensive therapy with fluid replacement, infusion of electrolytes and management of acid-base balance. Results：The total effective rate ranked from 96.6% （ group A） ,82.7% （ group B） to 78.2% （ group C）. Group A responded best to the medication（ P 〈 0.05 ）. Conclusion ： Ganciclovir plus cimetidine may be more effective in treatment of infants with rotavirus enteritis than single dose in clinic.
出处
《皖南医学院学报》
CAS
2009年第5期359-361,共3页
Journal of Wannan Medical College
