摘要
目的：探讨更昔洛韦配伍西咪替丁对婴幼儿轮状病毒性肠炎的治疗效果。方法：将婴幼儿轮状病毒性肠炎86例随机分为3组，治疗组用更昔洛韦5mg／（kg·d）、西咪替丁10～15mg／（kg·d）静脉滴注，对照1组用西咪替丁10～15mg／（kg·d）静脉滴注，对照2组用更昔洛韦5mg／（kg·d）静脉滴注。3组均1次／d，3d为1疗程。结果：治疗组、对照1组、对照2组总有效率分别为93．3％、75．0％、85．7％。治疗组与对照1组总有效率比较，有显著性差异（P＜0．05）；治疗组与对照2组总有效率比较无显著性差异（P＞0．05）；3组在用药后症状改善时间上有显著性差异（P＜0．01）。结论：更昔洛韦配伍西咪替丁治疗婴幼儿轮状病毒性腹泻疗效显著。
Objective ：evaluate the curative effect of ganciclovir combined with cimetidine on infants with rotavirus enteritis. Methods： 86 infant patients were divided randomly into three groups： observed group （ganciclovir plus cimetidine） and two control groups （cimetidine and ganciclovir respectively）. Medication protoeol; intravenous drip once a day, 3 days for a course of treatment. Result： The total effective rates of the observed, cimetidine and ganciclovir groups were 93.3%, 75.0% and 85. 7% respectively, of which, the results between the observed and the cimetidine had significant difference （P〈0.05） while no significant difference existed between the observed and the ganciclovir （P〉0.05） ; in addition, the time spans for symptom relief among three groups after medication had significant difference （P〈0.01）. Conclusion： The combined application of ganciclovir with cimetidine bas remarkable curative effect on the infant patients with rotavirus enteritis.
出处
《陕西医学杂志》
CAS
北大核心
2007年第1期100-101,109,共3页
Shaanxi Medical Journal
