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CD133分子与造血干/祖细胞和癌干细胞之间的关系 被引量：1

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摘要 越来越多的实体瘤癌干细胞(CSCs)研究中鉴定分离出含有CD133+的CSCs亚群。深入了解CD133+分子的生物学特性及在细胞与肿瘤信号转导、药物耐受和放化疗抵抗等的相关性,将有助于靶向治疗CSCs。本文就CD133分子与造血干/祖细胞(HSPC)和CSCs之间的关系及其耐药机制的研究进展作一综述。
作者 胡卫华 窦骏
机构地区 东南大学基础医学院病原生物学和免疫学系
出处 《微生物学免疫学进展》 2009年第3期63-66,共4页 Progress In Microbiology and Immunology
基金 江苏省六大人才高峰药业项目(医药行业D14)
关键词 CD133分子 造血干细胞 癌干细胞 耐药治疗
分类号 R730.2 [医药卫生—肿瘤] R730.5 [医药卫生—肿瘤]
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微生物学免疫学进展
2009年 第3期

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