摘要
目的:探讨韧带样型纤维瘤病(DTF)的临床病理特征及诊断与鉴别诊断。方法:对21例DTF进行临床病理观察及免疫组化染色。结果:组织学特点:瘤细胞由梭形的纤维母细胞和胶原纤维组成,核分裂相少见,向周围组织内浸润性生长。免疫组化:21例DTF瘤细胞胞浆均弥漫性表达SMA和Vim,部分病例中的瘤细胞散在性表达S-100和Desmin,而CD34和CD117均阴性。结论:DTF是一种具有局部侵袭性的中间型肿瘤,联合应用SMA、Vim、Desmin、S-100、CD34和CD117标记物对其诊断和鉴别诊断具有重要意义。
Objective： To explore the clinicopathological features, diagnosis and differential diagnosis of desmoid type fibromatosis.Methods： 21 cases of DTF was studied using route histopathologyic and immunohistochemical staining.Results： Desmoid type fibromatosis were consist of spindle fibroblasts in a varied of collagenous background.There are few mitosis can be detected, and the tumor show a pattern of infiltration the around tissues.All 21 cases expressed positive for SMA and Vim with cytoplasm staining,but negative for CD34andCDl17. Some cases expressed focal reaction for S-100 and desmin.Conclusions： Desmoid type fibromatosis is an intermediate （locally aggressive） tumor, combined with SMA, Vim,desmin,S -100, CD34andCD117 can make a great significance in diagnosis and differential diagnosis.
出处
《安徽卫生职业技术学院学报》
2009年第5期15-16,共2页
Journal of Anhui Health Vocational & Technical College
