摘要
目的:观察玻璃酸钠(Sodium Hyaluronate,SH)对慢性溃疡创面愈合的作用。方法:治疗组对44例患者的慢性溃疡创面局部彻底清创后,用玻璃酸钠进行涂敷,无菌敷料覆盖;对照组同期随机对另20例慢性溃疡创面用0.9%生理盐水进行局部湿敷。观察创面愈合时间、肉芽、上皮生长及不良反应情况。结果:治疗组创面不适感消失早,脓性分泌物少,肉芽组织生长快,无过度增生现象。溃疡面愈合时间:治疗组较对照组缩短7～10d。经统计学处理,差异著性(P<0.01)。结论:SH有明显促进慢性溃疡创面愈合的作用,且愈合时间短、愈合质量好。
Objective： To observe the effect of the glass sodium （sodium hyaluronate, SH） on chronic wound ulcers healing. Method ： 44 cases of patients with chronic ulcers in the local debridement, local sodium glass coating, sterile dressing coverage were grouped as the treated group and in the same period, and another 20 eases of chronic ulcer wound with normal saline 0.9% cm local wet, grouped as the controlled group. Then their wound healing time, wound granulation, epithelial growth and adverse circumstances were observed. Result： The treated group had their positive circumstances of an early disappearance of discomfort, little purulent discharge, rapid growth of granulation tissue and no over-proliferation. The surface ulcer healing time was 7 to 10 days shorter in the treatment group than that in the controlled group. , The difference was statistically significant （P 〈 0.01 ）. Conclusion： SH significantly promotes the healing of chronic ulcer wounds, and their healing time is short and healing quality is good.
出处
《药物流行病学杂志》
CAS
2009年第5期321-323,共3页
Chinese Journal of Pharmacoepidemiology
