摘要
脑钠肽(Btype natriuretic peptides BNP)主要由心脏分泌的循环激素,具有扩血管﹑利钠﹑利尿﹑抑制肾素﹑醛固酮分泌的作用。急性心肌梗塞早期BNP即明显升高,对急性心肌梗塞患者预后有很好的指导作用;心肌活动指数(myocardial performance index MPI)因不受超声条件、心脏几何形态、心室收缩及舒张压等影响,较之传统左室射血分数更为客观、准确,已被广泛应用于评价心功能。脑钠钛作为神经内分泌激素,心肌活动指数作为机械因素联合用于评价急性心肌梗死患者的预后及筛检急性冠脉事件的高危患者将起到更加重要的作用,本文现将两项指标在AMI最新研究进展作一综述。
B-type natriuretic peptides（BNP） is a cardiac hormone that is secreted mainly from the ventricles, it has many biological effects, including vasodilation,natriuresis,diuresis,inhibition of both the rennin and aldosterone. The plasma BNP level increases rapidly and markedly just after the onset of acute myocardial infarction （AMI）. This could be a satisfactory guideline to predict the prognosis of acute myocardial infarction. Myocardial performance index was hardly effected by the transonogram condition, heart geometry, ventricular contraction and diastole, etc. To compare with orthodox left ventricular ejection fraction, it was generally used to evaluate cardiac function on account of its more objective and accuratissime. B-type natriuretic peptides as neuroendocrine hormone and myocardial performance index as mechanical agents could play a very important roles in this area in which they are combinly used to evaluate the prognosis of AMI patients and to screen the high risk group about acute coronary artery events from “normal”people. This text aims at reviewing the latest research progress about the function of BNP and Tei index in AMI.
出处
《现代生物医学进展》
CAS
2009年第17期3381-3383,共3页
Progress in Modern Biomedicine
关键词
脑钠肽
急性心肌梗塞
TEI指数
B type natriuretic peptides （BNP）
Acute myocardial infarction（AMI）
Tei index
