摘要
目的:考察麻黄与甘草酸碱对药在麻杏石甘汤中配伍前后麻黄碱与甘草酸提取量的变化规律。方法:采用高效液相色谱法对麻黄,甘草单味药提取液,麻黄甘草对药提取液及全方提取液中麻黄碱和甘草酸提取量进行测定。结果:各样品液中麻黄碱变化不明显,全方中甘草酸提取量较单味药及对药提取药液降低。结论:酸碱对药麻黄、甘草在配伍后麻黄碱与甘草酸基本不形成大分子复合物。
Objective： To investigate the change regularity of ephedrine and glyrihhzine acid in Ephedra sinila and Glycyrrhiza uralencis pair medicines and in Maxing Shigan decoction. Method ： The contents of ephedrine and glyeyrrhizic acid were determined by HPLC in samples of E. sinica extracts, G. uralencis extracts, pair medicines extracts of Maxing Shigao decoction sinica and G. uralencis, and extracts of E. sinica. Result： There were no significant difference in ephedrine contents amoung different samples; the contents of glyeyrrhizie acid were lower in decoctions of Maxing Shigan decoction than in G. uralencis decoction and pair medicines extracts. Conclusion： Macromolecular complex was NOT formed by ephedrine and Glycyrrhizic acid in decoctions containing pair medicines of E. sinica and G. uralencis.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2009年第19期2466-2468,共3页
China Journal of Chinese Materia Medica
基金
国家自然科学基金项目(30472125)
关键词
麻黄
甘草
酸碱对药
麻杏石甘汤
配伍化学
Ephedra sinica
Glycyrrhiza uralencis
acid-alkaline pair medicine
Maxing Shigan decoction
compatability chemistry
