摘要
本文应用胃癌单抗MG_7、MGd_1对50例胃癌、24例浅表性胃炎进行PAP免疫组化染色,MG_7、MGd_1在胃癌中的阳性率分别为92%和90%,而浅表性胃炎阳性率分别为阴性和4%,表明MG_7、MGd_1对胃癌有较高的特异性。两株单抗联合检测胃癌的阳性率达96%,提示联合检测可提高胃癌的诊断率。
50 caese of gastric carcinoma and 24 caese of superficial gastritis were studied by PAP immunohistochemical staining,with monoclonal antibody MG_7,MGd_1 for determining the associated antigen of gastric carcinoma. Among the 50 cases of gastric carcinoma,the positive rates of MG_7,MGd_1 were 92%,90%;whereas in the cases of superficial gastritis,those were 0% and 4% respectively.These results suggest a high specificity of MG7,MGd1 for gastric carcinoma.When the two monoclonal antibodies were used together,the positive rate was as high as 96%.So the combined use would be of more diagnostic value.
出处
《昆明医学院学报》
1990年第3期45-47,共3页
Journal of Kunming Medical College
关键词
胃肿瘤
单克隆抗体
免疫组化
Gastric carcinoma
Monoclonal antibody
Immunohistochemistry
