摘要
目的探讨伴鼻息肉的慢性鼻及鼻窦炎(chronic sinusitis with nasal polyps,CRSwNP)患者变应原皮肤点刺试验(skin prick test,SPT)与临床特征的相关性。方法对60例CRSwNP患者(CRSwNP组)和40例无变应性疾病及家族史的鼻中隔偏曲患者(对照组)进行变应原SPT,并与临床特征的相关性进行统计学分析。结果CRSwNP组及对照组变应原SPT总阳性率分别为81.7%和17.5%(χ2=40.104,P<0.01),其中CRSwNP组吸入变应原阳性率为3.3%,食物变应原和吸入变应原阳性率为70%,食物变应原阳性率为8.3%;常年性变应原和季节性变应原阳性率为76.2%,常年性变应原阳性率为16.7%,季节性变应原阳性率为7.1%。不同分型分期CRSwNP患者间变应原阳性率有显著差异(χ2=11.360,P=0.010),有前期手术史者变应原SPT阳性率高于无前期手术史者(χ2=4.156,P=0.041),变应原SPT阳性率与鼻部变应性症状不相关(χ2=1.718,P=0.633)。结论CRSwNP组变应原SPT阳性率高于正常对照组,与CRSwNP的病程、病变范围及预后有关,与鼻部变应性症状无相关性。
OBJECTIVE To investigate the relationship between the skin prick test and clinical characteristics in patients with chronic sinusitis with nasal polyps （CRSwNP） . METHODS Sixty cases with CRSwNP and 40 control samples underwent skin prick test with standardized allergens provided by AllergoPhamar Company, the results and their clinical characteristics are analyzed. RESULTS The positive rate of skin prick test was 81.7% and 17.5% in CRSwNP group and control group respectively x2 =40.104, P〈0.01~） . The total positive rate of inhalant antigens and food allergens is 70%. The positive rate of food allergens and inhalant antigens is 8.3% and 3.3% respectively in CRSwNP group. The results of skin prick test have statistical significance between the defferent stages of CRSwNP x2=11.360, P=0.010） and were not correlated with the symptoms of allergic rhinitis x=1.718, P=0.633） . CONCLUSION The positive rate of skin prick test of CRSwNP group is higher than that of control group, and was related with clinical stages and extant, have no correction with symptoms of allergic rhinitis.
出处
《中国耳鼻咽喉头颈外科》
北大核心
2009年第8期444-446,共3页
Chinese Archives of Otolaryngology-Head and Neck Surgery
基金
广西壮族自治区科学基金(桂科青0728040)
