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MAGE-A1的研究进展

Research progress on MAGE-A1
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摘要 MAGE—A1是一种肿瘤特异性抗原，很多研究表明它可以作为肿瘤免疫治疗的靶抗原。 Mage-A1 is a kind of tumor specific antigen. Many studies indicate that it can be a target antigen for tumor immunotherapy. This article summarizes the expression of Mage-A1 in tumors and its promising clinical practice in the tumor immunotherapy.
作者 李小琳 廖红
机构地区 广西医科大学组织胚胎学教研室
出处 《中国临床新医学》 2009年第8期876-879,共4页 CHINESE JOURNAL OF NEW CLINICAL MEDICINE
基金 广西科技厅基金课题(桂科基0575059)
关键词 肿瘤 MAGE-A1 免疫治疗 Tumor MAGE-A1 Immunotherapy
分类号 Q753 [生物学—分子生物学]
  • 相关文献

参考文献12

  • 1李秋泽,董子明,赵国强,彭培立,赵洁.黑色素瘤抗原基因MAGE-1、MAGE-3和抑癌基因p53在肺癌中表达的研究[J].现代肿瘤医学,2007,15(8):1106-1108. 被引量：8
  • 2闫宏亮,王禾,李欣,刘贺亮.膀胱癌肿瘤/睾丸抗原相关基因的表达[J].第四军医大学学报,2005,26(11):1026-1028. 被引量：1
  • 3Chiurazzi P,,Neri G.Reaction of silencal genes and transcriptional therapy[].Cytogenetic and Genome Research.2003
  • 4Science . 1991
  • 5Akcakanat A,Kanda T,Tanabe T.Heterogeneous expression of GAGE,NY-ESO-1,MAGE-A and SSX proteins in esophageal canc-er:Implications for immunotherapy[].International Journal of Cancer.2006
  • 6Zhang Yuqing,Li Qiang,Liu Ning,et al.Detection of MAGE-1,MAGE-3and AFP mRNAs as multimarker by a real-time quantitative PCR Assay:a possible predictor of hematogenous micrometastasis of hepatocellular carcinoma[].Chinese Journal of Clinical Oncology and Rehabilitation.2008
  • 7Akcakanat A.MAGE-A1,GAGE and NY-ESO-1cancer/testis anti-gen expression during human gonadal development[].Human Reproduction.2007
  • 8Wischnewski F,Pantel K,Schwarzenbach H.Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1,-A2,-A3,and-A12in human cancer cells[].Molecular Cancer Research.2006
  • 9van der Bruggen P,Traversari C,Chomez P,et al.A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma[].Science.1991
  • 10Baylin SB,Herman JG.DNA hypermethylation in tumorigenesis: epigenetics joins genetics[].Trends in Genetics.2000

二级参考文献17

  • 1喻伦银,王虹,毕勇毅,刘铭球,邹祖玉,张正彬.p53基因突变与肺癌发生的早期遗传学损害[J].中华医学遗传学杂志,1996,13(3):161-163. 被引量：6
  • 2ELke J, Dirk J, Knuth Alexander. Clinical cancer vaccine trials[J]. Curr Opin Immunol, 2002,14(2): 178 - 182.
  • 3Scanlan MJ, Simpson A J, Old LJ. The cancer/testis genes: Review, standardization, and commentary[J]. Cancer Immunity,2002,4(1):1-15.
  • 4Chakraborty NG, Chattopadhyay S, Mehrotra S, et al. Regulatory T-cell response and tumor vaccine-induced cytotoxic T lymphocytes in human melanoma[J]. Hum Immunol, 2004,65(8):794 - 802.
  • 5Chi SN, Cheung NK, Cheung IY, et al. Expression of SSX-2 and SSX-4 genes in neuroblastoma[J]. Int J Biol Markers, 2002,17(4):219-223.
  • 6Jungbluth AA, Chen YT, Stockert E, et al. Immunohistochemical analysis of NY-ESO-1 antigen expression in normal and malignant human tissues[J]. Int J Cancer, 2001,92(6):856 - 860.
  • 7Jager E, Nagata Y, Gnjatic S, et al. Monitoring CD8 T cell responses to NY-ESO-1: Correlation of humoral and cellular immune responses[J]. Proc Nail Acacl Sci USA, 2000, 97(7):4760 - 4765.
  • 8Fischer C,Gudat F,Stulz P,et al.High expression of MAGE-3 protein in squamous-cell lung carcinoma[J].Int J Cancer,1997,71(6):1119-1121.
  • 9Peifer GP.p53 mutational spectra and the role of methylated CpG sequences[J].Mutat Res,2000,450(1-2):155-166.
  • 10Kersting M,Friedl C,Kraus A,et al.Differential frequencies of p16(INK4a)promoter hypermethylation,p53 mutation,and Kras mutation in exfoliative material mark the develop ment of lung cancer in symptomatic chronic smokers[J].J Clin Oncol,2000,18(18):3221-3229.

共引文献7

中国临床新医学
2009年 第8期

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