摘要
目的探讨千扰素联合中药治疗儿童病毒性肺炎的临床疗效的评价。方法对116例病毒性肺炎在常规对症治疗的基础上，治疗组58例加用干扰素c62b，每次5×10^4 IU／kg肌肉注射（最大量1×10^6IU），每日一次，并口服中药清气化毒饮或定喘汤，与对照组58例使用利巴韦林每日10～15mg／kg对照观察。结果两组患儿治疗1周后，治疗组有效率96．6％，对照组有效率63．8％，两组疗效比较有显著性差异，且治疗组发热，咳嗽，喘憋，肺哆音等症状消失时间明显短于对照组（P〈0．01）。结论干扰素联合中药治疗病毒性肺炎在改善症状，缩短病程和提高治疗效果方面明显优于对照组，且用药安全，未发现明显的副作用，值得在临床推广应用。
Objective To explore the clinical efficacy of the combined use of interferon and Chinese herbal medicine in the treatment of children with virus pneumonia. Methods 116 children of virus pneumonia were randomly divided into two groups with 58 cases in each group. In addition to symptomatic treatment, interferon α2b 5 ×10^4 IU/kg im（ biggest dosage 1×10^6 IU/kg） , qd and Chinese herbal medicine qingqihuaduying or dingchuantang were administered in combined treatment group, ribavirin was given at 10 - 15 mg/kg, qd. in control group. Results the treatment efficiency was 96.6% in combined treatment group and 63.8% in control group（ P 〈0.01 ） after one week treatment. Conclusion The combined use of Chinese herbal medicine and interferon significantly improves symptoms, shortens the course of disease and increases cure rate without obvious adverse effect in the treatment of children with virus pneumonia. The treatment schedule is worthy of being recommended for clinical application.
出处
《临床和实验医学杂志》
2009年第9期23-24,共2页
Journal of Clinical and Experimental Medicine
关键词
干扰素
中药治疗
病毒性肺炎
儿童
Interferon α2b
Chinese herbal medicine
Virus pneumonia
Children
