摘要
目的:观察α-干扰素雾化吸入对老年康复病人呼吸道感染的预防作用。方法:给予33例老年康复病人雾化吸入α-干扰素10万U加生理盐水20 ml,每天20 min,每月15 d,共12个月。观察雾化吸入前1年、雾化吸入后1年呼吸道感染次数以及雾化吸入前后免疫球蛋白IgGI、gAI、gM,补体C3、C4等体液免疫指标的变化。结果:33例老年康复病人雾化吸入α-干扰素后呼吸道感染的次数较雾化吸入前显著减少(P<0.01),IgGI、gAI、gM较吸入前显著增加(P<0.05),而补体C3、C4较雾化吸入前显著减少(P<0.05)。结论:雾化吸入α-干扰素对老年康复病人呼吸道感染有预防作用。
Objective To evaluate the preventing effect of aerosol α-interferon inhalation on respiratory infection in old patients.Methods 33 old patients were inhalated with a-interferon at a dose of 100 thousand units,20 min·d^-1 , and 15 days a months. The overall treating time was 12 months. Immunogical indices,namely： IgG, IgA,IgM, C3 and C4 were detected. The frequency of respiratory tract infection was compared between pre-inhataltion and post-treatment in the same patients. Re. suits After aerolsol inhalation,the frequency of respiratory infection decreased（ P 〈 0.01 ）, IgG, IgA and IgM increased,and C3 and C4 declined, respectively. Conclusion Aerolsol inhalation of α-interferon may prevent respiratory infection in o1d patients.
出处
《东南大学学报（医学版）》
CAS
2006年第2期120-121,共2页
Journal of Southeast University(Medical Science Edition)
