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腹腔镜切除大肠癌80例临床对比研究 被引量:3

CLINICAL COMPARATIVE STUDY OF LAPAROSCOPIC RADICAL AND TRADITIONAL RADICAL OPERATION ON COLORECTAL CARCINOMA
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摘要 目的探讨腹腔镜结直肠癌切除术的临床疗效和微创优势。方法采用与同期开腹手术相比较的方法,将2001年10月—2008年11月行结直肠癌切除的患者分为腹腔镜手术组(80例)和开腹手术组(82例),比较二组标本的病理结果,围术期情况,评价各组的肿瘤根治性,手术安全性、术后恢复情况、医疗费用和近期随访结果。结果腹腔镜手术组术中出血量明显减少(P<0.05),术后应用吗啡镇痛的剂量明显减少(P<0.01),术后离床时间和术后住院日数明显减少(P<0.05)。肿瘤根治性相关临床病理学结果提示二组患者完全可以达到相同的根治程度,二组术后并发症比较差异无统计学意义(P>0.05)。腹腔镜组未发现Trocar穿刺部位及小切口部位肿瘤种植转移,二组在局部复发、远处转移、腹盆腔广泛转移和病死率差异无统计学意义(P>0.05)。腹腔镜手术组费用显著高于开腹手术组(P<0.05)。结论腹腔镜结直肠癌切除术近期疗效,微创等方面较开腹手术有较明显的优势,具有可行性。 Objective To compare the effects of laparoscopic redical and traditional redical operation on colorectal carcinoma.Methods From Oct 2001 to Nov 2008,operation safety,recovery,complications,expenditure,lymph nodes clearance and short term outcome of patients undergoing either laparoscopic(lapa group 80 cases)or open operation(ope group 82 cases)for colon and rectal carcinoma were compared.Results The blood loss was significantly diminished(P〈0.05),anti-nociceptive drugs was significantly decrease in lapa group (P〈0. 05) ; and time to resume early activity and hospital stay in lapa group was significantly shorter than that in ope group (P〈0. 05); clinical pathology finding showed the same radical cure for the two groups and similar complications in the two groups (P〈0.05). No significant difference between the two groups was observed in the local recurrence, metaehronous metastases and mortality (P〈0. 05). Conclusion Laparoscopic radical carcinosectomy for colorectal cancer can be performed safely, effectively with the advantages of minimal invasiveness.
出处 《中国煤炭工业医学杂志》 2009年第8期1173-1175,共3页 Chinese Journal of Coal Industry Medicine
关键词 结直肠癌 腹腔镜 切除术 colon carcinoma rectal carcinoma laparoscope resection operation
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