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补体损伤类鼻疽杆菌外膜的实验研究 被引量:1

Laboratory Investigation on the Membrane attacking Function of Complement to Pseudomonas pseudomallei
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摘要 分离获得的类鼻疽杆菌在抗血清和补体的作用下,进行了青霉素药敏试验和L型菌的形成试验。结果表明,类鼻疽杆菌虽然具有抵抗补体杀灭的特性,但补体激活所形成的膜攻击物可损伤类鼻疽杆菌的外膜,从而增强了其对青霉素的敏感性。从这一意义上讲,补体在抗类鼻疽杆菌感染的机制中已完成了杀菌的第一步。 The penicillin sensitivity test and L phase test for the Pseudomonas pseudomallei were conducted to clarify the role of serum antibody and complements in bacteriocidal action. The results showed that the susceptibility of Pseudomonas pseudomallei to penicillin G increased after being treated with normal sera, suggesting the damage action of membrane attacking complex to the outer membrane can be activated by complements in despite of the P. pseudomallei had proven to be resistant to the complement bacteriocidal activity.
出处 《中国兽医学报》 CAS CSCD 北大核心 1998年第4期349-350,共2页 Chinese Journal of Veterinary Science
关键词 类鼻疽杆菌 外膜 补体 损伤 Pseudomonas pseudomallei  outer membrane complement damage
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