摘要
目的探讨在大学生人群中注射乙肝疫苗(YDV),控制乙肝病毒的传播,免疫效果和安全性,为制定大学生免疫策略提供依据。并观察乙肝疫苗0、1、6注射前后抗体阳转率。方法在2008年入校的新生中随机选择健康状况良好、乙肝两对半全部为阴性的部分学生600名,按0,1,6个月免疫程序,接种北京生物制品研究所生产的YDV,每剂10μg/mL。结果免疫后分期观察其阳转率,并分析阳转率与性别及免疫后时间是否有关。结论通过对大学生进行乙肝疫苗接种效果分析。说明在大学生青年人群中进行乙肝疫苗接种,对于控制乙肝高流行状态,减少我国乙肝感染带来的巨大经济损失有着重要的意义。其抗-HBs持续时间有待进一步观察。
Objective Discuss the immunity effect and security through inoculating YDV in the academicians to control the spread of hepatitis B vaccination and supply the gist of estabish the immunity policy for the academicians. Observe the antibody up to snuff after inoculating YDV in the first month,the second month and the sixth month . Method Choss 600 healthy freshman coming into HuBei university of TCM in 2008 at random and inoculate YDV to them in the first month,the second month and the sixth month .The YDV has been manufactured by Beijing biology product graduate school.Each bottle of the YDV has 10μg/mL.Result content. Then observe the rate of the antibody up to snuff by stages . At the same time analyse the rate bearing on sex and the time of inoculation whether or not. Conclusion Illuminate the purport across analysing the effect about inoculating YDV in youth of the academicians.By inoculating YDV,it can control the widely spread of hepatitis B vaccination.And it also can lessen the enormous economy damnify of infected by hepatitis in our country.After inoculating YDV,the antibodyJs duration needs more observation.
出处
《医学信息》
2009年第9期1805-1807,共3页
Journal of Medical Information
关键词
乙肝疫苗
乙肝表面抗原
免疫效果
抗体阳转率
Hepatitis B vaccination
HBsAg
Protective efficacy
Positive rates of anti-HBs