摘要
目的:探讨垂体后叶素联合单硝酸异山梨酯治疗冠心病或高血压病合并大咯血的安全性及有效性。方法:对34例冠心病或高血压病合并大咯血患者在其他药物治疗无效的情况下,予垂体后叶素联合单硝酸异山梨酯治疗,观察患者自觉症状、出血、血压及心电图的变化情况。结果:34例中显效17例,有效14例,无效3例,止血总有效率为91.2%。4例出现不良反应,不良反应发生率为11.8%。本组治疗前与治疗后血压及心电图变化比较差异无统计学意义(P>0.05)。结论:垂体后叶素联合单硝酸异山梨酯治疗冠心病或高血压病合并大咯血止血速度快、效果确切、安全,且不良反应少。
Objective:To study the safety and efficacy of pituitrin combinded with isosorbide mononitrate in treating coronary heart disease or hypertension complicated with massive hemoptysis. Methods: 34 patients with massive hemoptysis and with coronary heart disease or hypertension received the combination therapy of pituitrin and isosorbide mononitrate when other medication treatment failed. The patients symptoms, bleeding, blood pressure and electrocardiogram changes were observed. Results:17 cases had excellent results, 14 cases had effective results and 3 cases had invalid result. The efficacy rates were 91.2%. Only 4 cases had adverse reactions( 11.8% ). Changes in blood pressure and electrocardiogram pre-and post treatment showed no significant difference (P 〉 0.05). Conclusion: Pituitrin combinded with isosorbide mononitrate in treating coronary heart disease or hypertension complicated with massive hemoptysis can achieve hemostasis faster and as a safe and effective approach with less adverse reactions.
出处
《临床误诊误治》
2009年第8期1-2,共2页
Clinical Misdiagnosis & Mistherapy