摘要
目的：阐明血脂与脑血管病分类亚型的关系。方法：检测了２０８例脑血管病患者血清血脂７项指标含量。并与对照组５０例结果进行比较。ＴＧ、ＴＣ及ＨＤＬ－Ｃ采用酶法测定，ＡＰＯＡ－１、ＡＰＯＢ１００及ＬＰ（ａ）用免疫多点定标法测定，ＬＤＬ－Ｃ由ＴＧ、ＨＤＬ－Ｃ结果按公式计算。结果：脑梗塞（ＣＩ）患者ＴＧ、ＴＣ、ＬＤＬ－Ｃ、ＡＰＯ１００及ＬＰ（ａ）含量显著高于对照组，其ＴＧ、ＡＰＯＢ１００、含量也显著高于脑出血组，且ＬＰ（ａ）与ＡＰＯＢ１００，ＨＤＬ－Ｃ相关，复发ＣＩ亚组ＴＣ、ＬＤＬ－Ｃ、ＡＰＯＢ１００含量，首发及老年ＣＩ亚组ＴＧ、ＴＣ、ＡＰＯＢ１００含量显著高于对照组。结论：血清ＴＧ、ＴＣ、ＬＤＬ－Ｃ、ＡＰＯＢ１００及ＬＰ（ａ）水平升高是ＣＩ的危险因素，其中ＴＣ、ＬＤＬ－Ｃ、ＡＰＯＢ１００对复发ＣＩ危险性大，而首发及老年ＣＩ可能主要与ＴＧ、ＴＣ。
Objective:The aim of this study was to identify the role of serum lipids in cerebrovascular disease(CVD).Method:We investigated and analyzed the blood levels of lipids in 105 patient s with cerebral infarction(CI),103 patients with cerebral hemorrhage(CH).Results:The results showed that patients with CI had significantly higher levels of TG,TC, LDLC,APOB100 and LP(a) than controls, the TC,LDLC and APOB100levels were much higher in patients with recurrent cerebral infarction(RCI) than those in controls,the levels of TG,TC and APOB100 were significantly higher in patients with the first cerebral infarction (FCI) and those with the age more than 60 years when compared with control subjects. The TG,APOB100 levels of CI group were significantly elevated when compared with those of CH group. Condusion:The results suggest that the higher serum TG,TC,LDLC,APOB100and LP(a) levels were common risk factors for CI, the high serum TC, LDLC and APOB100levels could be important risk factors for RCI. Our study also indictated the high serum TG, TC, APOB100 levels might affect patients of FCI and CI with the age over 60 years. In the meantime, we also find whether LP(a) is a risk factor in patient with RCI remains unclear.
出处
《卒中与神经疾病》
1998年第2期73-76,共4页
Stroke and Nervous Diseases
