摘要
目的通过对男性生殖道标本中支原体、衣原体的检测,分析其耐药性,提出合理的用药对策。方法采用支原体鉴定药敏试剂盒,衣原体采用单克隆抗体胶体金法检测其抗原,对320例男性生殖道感染者进行培养检测及药敏试验。结果320份标本中检出支原体阳性率28.4%,沙眼衣原体阳性率5.6%,其中解脲脲支原体阳性率占19.7%。人支原体阳性率占8.8%,解脲脲支原体和人支原体混合感染阳性率为3.1%,支原体和衣原体混合感染阳性率为2.2%;支原体对抗菌药物药敏结果显示,罗红霉素和阿奇霉素有较高的耐药率,多西环素和米诺环素有较好的抑菌能力。结论支原体、衣原体感染病例在增加,耐药株也在增加,对男性支原体感染者应选用敏感率较高的多西环素、米诺环素,对耐药率高的罗红霉素等,用药时要慎重。
OBJECTIVE To detect the Mycoplasma ureaplasma and Chlamydia infection in male urogenital system, and analyze their antibiotic resistance analysis and therapeutic strategies. METHODS Mycoplasma and their drug sensitivity were detected by culture method and analyze Chlamydia and Ureaplasma antigen with monoclonal antibody colloid gold assay. RESULTS From 320 specimens there were 18 cases who had Chlamydia trachomatis （5.6%） and 91 cases who had Mycoplasma （28.4%）. The single infection of Ureaplasma urealytilcum（Uu） and M. horninis（Mh） and Ct was in 63 cases （19.7% ） and 28 cases （8.8%）, respectively, Uu-β- Mh were 10 cases （3.1 % ） and Uu＋ Ct were in 7 cases （2.2 %）. The result of drug sensitivity showed：doxycycline and minocycline had the higher bacteriostatic ability. CONCLUSIONS With the growing number of Mycoplasrna, the resistant strains are incveasing. Experimental evidence showed doxycycline and minocycline can be used as the first choice for Mycoplasma and Ureaplasma infection, but roxithromycin be used carefully.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2009年第16期2206-2207,共2页
Chinese Journal of Nosocomiology
