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大肠同时多原发癌与大肠腺瘤癌变 被引量:2

Homochronous multiple primary cancer and canceration of adenoma of the large intestines
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摘要 目的探讨大肠同时多原发癌的发病情况及其与大肠腺瘤癌变的关系。方法连续观察可切除并经病理检查证实的大肠癌166例。结果 166例大肠癌中同时多原发大肠癌8例(4.8%),单发癌合并腺瘤43例(27.2%)。同时癌合并腺瘤4例,这4例同时癌共有腺瘤14处,其中2例的3处腺瘤癌变,8例同时多原发大肠癌的18处癌灶中直径小于3cm 的8处。结论大肠同时多原发癌并非罕见,且与腺瘤癌变有关。临床上不应满足于单发大肠癌病灶的发现。术前钡剂灌肠及术中探查均易漏诊。对全结肠行纤维结肠镜检查是提高诊断率的重要手段。 Objective To investigate the epidemiology of homochronous multiple primary cancer of the large bowl and its relation with adenoma.Method The postoperative course was followed-up in 166 cases suffering from resectable large bowl carcinoma.Result We discovered 8 cases(4.8%)of homochronous multiple primary cancer of large interstines.The single primary cancer coincided with adenoma in 43 cases(27.2%).At the same time 4 cases of homochronous multiple cancer have complicated by 14 adenomas(50%).The canceration of adenomas was found in 3 out of 14 benign adenomas in 2 out of the 4 cases(50%)of homochronous multiple carcinoma.There were altogether 18 cancer nidi in 8 cases of homochronous multiple primary carcinoma of the large intestines among them 8 cancer nidi were less than 3 cm in diameter.Conculsion Homochronous can- cer of large intestines is by no means exceptional,and there is an evidence that it may come from the canceration of adenoma.The colanoscopy is important means to raise the diagnostic rate of the adenoma of the large bowl.
出处 《中华普通外科杂志》 CSCD 1998年第4期210-211,共2页 Chinese Journal of General Surgery
关键词 大肠肿瘤 多原发性 腺瘤 癌变 Neoplasm,multiple primary Adenomatous plyposis coli Colonoscopy
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  • 1B. Mark Evers M.D.,Richard J. Mullins M.D.,Timothy H. Matthews M.D.,Walter L. Broghamer M.D.,Dr. Hiram C. Polk M.D.. Multiple adenocarcinomas of the colon and rectum[J] 1988,Diseases of the Colon & Rectum(7):518~522
  • 2Dr. John C. Reilly M.D.,Lawrence C. Rusin M.D.,Frank J. Theuerkauf M.D.. Colonoscopy: Its role in cancer of the colon and rectum[J] 1982,Diseases of the Colon & Rectum(6):532~538
  • 3R. J. Heald M.Chir. F.R.C.S.,H. J. R. Bussey Ph.D.. Clinical experiences at St. Mark’s Hospital with multiple synchronous cancers of the colon and rectum[J] 1975,Diseases of the Colon & Rectum(1):6~10

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