期刊文献+

肝素结合表皮生长因子样生长因子与动脉粥样硬化 被引量:4

暂未订购
导出
摘要 肝素结合表皮生长因子样生长因子(heparin—binding EGF—like growth factor,HB—EGF),又叫内皮细胞生长因子样因子,是一种内皮细胞生长因子,可以促进平滑肌细胞增殖、有丝分裂以及迁移,从而促进动脉粥样硬化的形成。国内外学者对其在动脉粥样硬化的发生机制以及和动脉粥样硬化的关系做了广泛深入的研究。
作者 刘红旗 谈敏
出处 《安徽医学》 2009年第8期982-984,共3页 Anhui Medical Journal
  • 相关文献

参考文献18

  • 1Fen Z, Dhadly MS, Yoshizumi M,et al.Structural organization and chromosomal assignment of the gene encoding the human heparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor.Biochemistry,1993,32(31 ):7932-7938.
  • 2Abraham JA, Damm D, Bajardi A, et al.Heparin-binding EGF- like growth factor: characterization of rat and mouse cDNA clones, protein domain conservation across species, and transcript expression in tissues.Biochem Biophys Res Commun, 1993, 190(1):125-133.
  • 3Feng J, Mehta VB, El-Assal ON, et al. Tissue distribution and plasma clearance of heparin-binding EGF-like growth factor (HB-EGF) in adult and newborn rats. Peptides, 2006,27 (6): 1589-1596.
  • 4Alison R, Laura V, Heather S, et al. Dual inhibition of ErbB1 (EGFR/HER1) and ErbB2 (HER2/neu).Eur J Cancer,2007,43 (3):481-489.
  • 5Elenius K, Paul S, Allison G, et al. Activation of HER-4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferation.EMBO, 1997,16 (6): 1268-1278.
  • 6Nishi E, Prat A, Hospital V, et al.N-arginine dibasic convertase is a specific receptor for heparin-binding EGF-like growth factor that mediates cell migration. EMBO,2001,20(13):3342-3350.
  • 7Lee KS, Park JH, Lee S,et al .HB-EGF induces delayed STAT3 activation via NF-kappaB mediated IL-6 secretion in vascular smooth muscle cell.Biochim Biophys Acta, 2007, 1773(11): 1637-1644.
  • 8Mehta VB, Besner GE.HB-EGF promotes angiogenesis in endothelial cells vis PI3-kinase and MAPK signaling pathways. Growth Factors,2007,25 (4):253-263.
  • 9Zhang H, Sunnarborg SW, McNaughton KK, et al. Heparinbinding epidermal growth factor-like growth factor signaling in flow-induced arterial remodeling. Circ Res, 2008,102( 10): 1275-1285.
  • 10Igura T, Kawata S, Miyagawa J, et al. Expression of heparinbinding epidermal growth factor-like growth factor in neointimal cells induced by balloon injury in rat carotid arteries.Arterioscler Thromb Vasc Biol,1996,16(12):1524-1531.

同被引文献42

引证文献4

二级引证文献15

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部