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丝裂霉素C联合自体角膜缘干细胞移植治疗翼状胬肉 被引量:2

Clinical study of auto-corneal limbus stem cell transplantation combined with Mitomycin C (MMC) for the treatment of pterygium
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摘要 目的观察翼状胬肉切除联合术中应用丝裂霉素C(MMC)+自体角膜缘干细胞移植治疗翼状胬肉的临床疗效。方法对48例51只眼翼状胬肉患者,行翼状胬肉切除,同时术中应用0.02%MMC联合自体角膜缘干细胞移植,术后随访胬肉复发情况。结果术后随访6~18个月,角膜创面愈合良好,视力均有不同程度提高,胬肉复发3眼(复发率5.88%)。结论翼状胬肉切除联合术中应用MMC+自体角膜缘干细胞移植治疗翼状胬肉,能明显降低术后复发率。 Objective To observe clinical efficacy of auto-corneal limbus stem cell transplantation combined with MitomycinC (MMC) for the treatment of pterygium. Methods Auto-corneal limbus stem cell transplantation combined with MitomycinC (0.02%MMC) after excision were performed in 48 patient (51eyes)with pterygium. The recurrency rate was observed over a 6-18 months follow-up period. Results All patients" cornea healed well, Visual acuity in patients were improved. Recurrence of pterygium was observed only in 3 eyes(5.88%). Conclusion Auto-corneal limbus stem cell transplantation combined with MMC is an effective therapy for pterygium. It can obviosly reduce the postoperative recurrent rate of pterygium.
出处 《安徽医学》 2009年第8期869-870,共2页 Anhui Medical Journal
关键词 翼状胬肉 丝裂霉素C 角膜缘干细胞移植 Pterygium Mitomycin C (MMC) Auto-corneal limbus stem cell transplantation
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参考文献4

  • 1王雨生.翼状胬肉的治疗及其并发症[J].国外医学:眼科学分册,1994,18(2):116-121.
  • 2Dus HS, Azuara BA.Limbal autograft transplantation in patients with unilateral corneal stem cell deficiency.Br J Ophthalmol, 2002,84(2) : 273.
  • 3程瑜,钟一声,孙静芬,周正申.翼状胬肉术中丝裂霉素不同留置时间的效果[J].眼外伤职业眼病杂志,2002,24(2):190-191. 被引量:21
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二级参考文献10

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