摘要
为探讨妊高征胎盘形态计量学特点，应用图像分析系统对２９例重度妊高征（妊高征组）和２９例正常妊娠（对照组）的胎盘床血管和胎盘绒毛进行形态计量学检测。结果：妊高征组胎盘绒毛具有合体细胞结节、细胞滋养细胞增生、绒毛基底膜增厚、纤维素样坏死和血管合体细胞膜的绒毛数与对照组相比差异显著（Ｐ＜００５）。妊高征组胎盘绒毛直径、周长和面积参数均显著低于对照组（Ｐ＜００５）。妊高征组胎盘床螺旋动脉妊娠生理性改变缺乏，管壁增厚、纤维素样坏死和急性动脉粥样化的发生率显著高于对照组（Ｐ＜００５）。妊高征组ＩＵＧＲ和围产儿病死率显著高于对照组（Ｐ＜００５）。提示胎盘床血管和胎盘形态学病变在妊高征的发病中可能起重要作用。
Objective:To study the morphological characteristics of the placenta in the severe pregnancy induced hypertension(SPIH).Methods:The morphometriology of uteroplacental bed vassels and placental villus were observed by image analysis in 29 cases of SPIH and 29 cases of normal term pregnancies(NTP) were examined to observe.Results:There were significant differences in the number of the villus with the syncytial knots,cytotrophoblasts,thickening of basal lamina,fibrinoid necrosis and vasculo-syncytial membranes between SPIH and NTP(all P<0.05).The diameter,perimeter and area of the villus in SPIH were significantly lower than those in NTP(all P<0.05).The incidence of the deficiency of physiological changes,the thick arterial wall fibrinoid necrosis,and acuta atherosclerosis of the spiral arteries of the uteroplacental bed in SPIH were significantly higher than those in NTP (all P<0.05).The incidence of IUGR and perinatal death in SPIH were significantly higher than those in NTP(all P<0.05).Conclusion:The morphological lesions of the uteroplacental bed vessels and the placenta may play an important role in the pathogenesis of PIH.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
1998年第4期221-222,共2页
Chinese Journal of Practical Gynecology and Obstetrics
基金
天津自然科学基金
关键词
胎盘
形态计量学
妊娠高血压
综合征
Pregnancy induced hypertension\ Placenta\ Uteoplacental bed\ Morphometry
