摘要
目的:探讨严重阴茎病变(畸形)的外科治疗方法。方法:62例患者年龄19～63岁(平均35岁),其中阴茎部分缺失4例,分别行阴茎缺损修复、阴茎延长术、尿道成形术;阴茎完全缺失3例,行阴茎再造术;阴茎严重弯曲22例,行"16点"弯曲矫正术;阴茎折断15例,1例保守治疗,14例分别修补阴茎海绵体、尿道海绵体,阴茎背深静脉结扎;假体植入术后并发症5例,包括假体从尿道穿出、水泵失灵、连接管断裂,勃起角度<60°和海绵体无法扩张,分别行假体取出、修补尿道裂口,更换新的假体,切除纤维化的瘢痕再次植入假体;阴茎完全离断4例,行阴茎再植术;撕脱伤3例,行皮瓣回植和游离植皮;阴茎Paget病6例,行病灶切除、游离植皮和阴茎埋入阴囊。结果:该组随访3个月至4年,平均9个月,4例阴茎部分缺失患者,2例术后阴茎外形满意,性功能恢复,较满意和不满意各1例。阴茎完全缺失3例术后外形满意,排尿好,1例不满意。22例阴茎严重弯曲均被矫正,1例复发。阴茎折断15例,失访1例,14例获得随访,性功能均恢复,术后并发症5例,分别为轻度弯曲、性交痛、皮下硬结、硬度差、性快感差,未作进一步处理。假体植入术后并发症5例,再次手术均成功,术后均能进行性生活,4例配偶满意,仅1例配偶不满意。阴茎完全离断4例,2例再植成功,2例坏死。撕脱伤3例植皮均获得成功。6例阴茎Paget病患者术后皮瓣均成活,随访2～4年,1例死于脑转移,5例无瘤存活至今。结论:该类病例需在泌尿男科手术的基础上,配合显微外科技术、皮瓣或皮肤移植技术等,设计个性化手术方案,能解决大多数患者的阴茎形态和勃起功能障碍,但部分患者仍不能达到理想的外形或功能,有待于寻求新的治疗方法。
Objective ： To investigate the effects of surgery treatment on serious penile lesions and malformation. Methods ： Sixty-two patients, aged from 19 to 63 years old （mean 35 ys） , were included in the study. Among them, 4 patients suffered from penis partial defection were respectively treated with restoring defective penis, penis lengthening and urethroplasty; three patients with penis completely missing were treated with penis reconstruction surgery; 22 cases with serious penile curvature were treated with the 16-dot plieation technique （Lue＇s procedure） ; 15 cases with penile fracture were treated with conservative treatment for 1 case and with patch penis, corpus spongiosum, and deep penile dorsal vein ligation for lg cases ; 5 cases with post-operative complications of 3-pieces of penile prosthesis, including the prosthesis perforating to the urethra, water pump failure, broken connection tube, erection angle 〈 60 ° and failure to expansion the corpus cavernosum, were treated by taking out prostheses, urethral repair cracks, replacement of the prostheses, excision of fibrosis scar and re-implantation prostheses respectively. Four cases with penis complete amputation were treated with the penis replantation; three cases of avulsion injury were treated with the replantation and free flap skin; 6 with Paget＇s disease of penises were treated with the lesion free skin buried in the scrotum and penis. Results： All these patients were followed up for 3 months to 4 years, with the average of 9 months. Among the 4 cases of penis partial defection, 2 patients were satisfied with the penile appearance and sexual function; 1 got some satisfactory and 1 was unsatisfied. Three cases with the loss of the penis completely were satisfied with both the postoperative appearance and urination, and 1 was not satisfied. Twenty-two cases of penile curvature deformities were corrected, and one case was recurrence. Fourteen of the 15 patients with penile fracture were followed, and all got the restoration of sexual function. Among them, 5 cases with post-operative complications, including mild bending, algopareunia, subcutaneous indu- ration, poor hardness and poor sexual pleasure, were not further treated, and another case lost; Five cases with post-operative complications of three-pieces penile prosthesis were treated successfully, and 4 of their spouses were satisfied with their sexual function after operation, only 1 of their spouse not satisfied. Among four cases with complete amputation of penis, two cases of penis were replanted successfully while two necrosis. Three cases with avulsion were treated with skin grafting successfully. All 6 cases with penile Paget＇s disease were followed for 2 - 4 years, and free skin grafts were all survival. One patient died of brain metastases 18 months after opera- tion and five cases were disease-free survival. Conclusion ： The patients should be treated based on the procedure of andrological and urological surgery, together with microsurgical, flap or skin graft technique. The urologist should design personalized surgical procedure. Most of the patient＇s penis shape and erectile dysfunction can be reconstructed by our procedures, but some patients can not achieve the desired appearance or function of penis. New approaches of the treatment ought to be developed to restore both of the shape and function for those severe injury of the penis.
出处
《中华男科学杂志》
CAS
CSCD
北大核心
2009年第8期693-699,共7页
National Journal of Andrology
基金
国家自然科学基金(30672110)
上海市科委基础研究重点项目(08JC1414000)
上海市科委环境条件计划项目(08140901700)~~
关键词
PAGET病
阴茎
阴茎假体
阴茎弯曲
阴茎折断
阴茎再植
皮瓣
Paget＇s disease
penis
penile prosthesis
penile curvature
penile fracture
penile replantation
skin graft
