摘要
目的:探讨复发性阴囊阴茎Paget病的复发因素、治疗方法和预后。方法:对收治的18例复发性阴囊阴茎Paget病的临床表现、治疗和预后进行回顾性研究,均行组织活检确诊后进行广泛切除术,深达深筋膜,术中冰冻和术后石蜡切片均为切缘阴性,7例淋巴结活检阳性患者均进行淋巴结清扫。结果:全部病例均获得随访,随访时间为6个月～8年,平均34个月。4例因远处转移死亡,其余14例随访期间未见再次复发。结论:对于无转移的复发性阴囊阴茎Paget病患者,局部再行广泛切除术同样是首选治疗,预后良好,对伴淋巴结转移的患者,需行局部淋巴结清扫。
Objective： To investigate the causes, therapeutic methods and prognosis of recurrent extramammary Paget＇s disease of the penis and scrotum. Methods： We retrospectively studied the clinical presentations, therapeutic methods and prognosis of 18 cases of recurrent penile and scrotal Paget~ disease, all diagnosed by biopsy and treated by surgical resection of the diseased sites. The incision reached the deep fascia. Frozen and olefin sections of the samples were pathologically examined to identify the involvement of the incisal edge. Seven cases had inguinal lymph node metastasis and underwent unilateral or bilateral inguinal lymph node resection. Results ： All the patients were followed up for 6 months to 8 years （ mean 34 months）. Four died of distant metastasis and the other 14 experienced no recurrence. Conclusion ： For the cases without metastasis of recurrent penile and scrota1 Paget＇s disease, extended lesion-resection is a preferred option and the prognosis is good. And those with local lymph node metastasis need to undergo local lymph node resection.
出处
《中华男科学杂志》
CAS
CSCD
北大核心
2009年第1期34-36,共3页
National Journal of Andrology
关键词
PAGET病
阴茎
阴囊
复发
Paget＇s disease
penis
scrotum
recurrence
