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肿瘤干细胞与胶质瘤细胞起源 被引量：3

Tumor stem cells and glioma initiating cells
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摘要 The tumor stem cell theory supposed that tumor stem cells are the origin of tumor abnormal proliferation,invasion,metastasis,drug resistance and recurrence.As the theory is put forward,it redefines the functions of classic stem cells in tumorigenesis.It is a great event for recent studies on glioma initiating cells as brain tumor stem cells were identified and isolated successfully.A lot of evidence from experiments in vivo and in vitro demonstrates that brain tumor stem cells might play an important role in glioma tumorigenesis.In this review,we discuss the relationship between tumor stem cells and tumorigenesis,and the research on the correlation between brain tumor stem cells and glioma genesis. The tumor stem cell theory supposed that tumor stem cells are the origin of tumor abnormal proliferation, invasion, metastasis, drug resistance and recurrence. As the theory is put forward, it redefines the functions of classic stem cells in tumorigenesis. It is a great event for recent studies on glioma initiating cells as brain tumor stem cells were identified and isolated successfully. A lot of evidence from experiments in vivo and in vitro demonstrates that brain tumor stem calls might play an important role in glioma tumorigenesis. In this review, we discuss the relationship between tumor stem cells and tumorigenesis, and the research on the correlation between brain tumor stem cells and glioma genesis.
作者 李平 钟雪云
机构地区 暨南大学医学院病理教研室
出处 《中国病理生理杂志》 CAS CSCD 北大核心 2009年第8期1652-1655,共4页 Chinese Journal of Pathophysiology
基金 国家自然科学基金资助项目(No.30670795)
关键词 肿瘤干细胞 神经胶质瘤 脑肿瘤干细胞 细胞分化 Tumor stem cells Glioma Brain tumor stem cells Cell differentiation
分类号 R730.2 [医药卫生—肿瘤]
  • 相关文献

参考文献22

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二级参考文献10

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共引文献10

同被引文献17

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引证文献3

二级引证文献29

中国病理生理杂志
2009年 第8期

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