摘要
目的探讨高血压患者脉搏波速度(PWV)及其影响因素。方法共入选179例,分为高血压组和非高血压组,使用VP-1000全自动动脉硬化测定仪测定其双侧肱踝PWV(BaPWV),并测定血脂各项,血肌酐、尿素氮,血尿酸及晨尿尿微量白蛋白。比较高血压组和非高血压组PWV及尿微量白蛋白。并将各因素与PWV进行多元逐步回归分析。结果高血压组右侧PWV(RPWV)均值为(1568±250)cm/s,左侧PWV(LPWV)均值为(1572±261)cm/s;非高血压组PWV均值分别为(1440±193)cm/s和(1440±202)cm/s。高血压组的PWV和尿微量白蛋白均明显高于非高血压组(P<0.01,P<0.05)。多因素分析显示年龄、收缩压、高血压、尿微量白蛋白与PWV独立相关。结论年龄、收缩压、尿微量白蛋白、高血压是PWV的独立影响因素。
Objective To investigate pulse wave velocity （PWV） in hypertensive patients and evaluate its related factors. Method 179 subjects were divided into hypertension（HTN） group and non-hypertension （NHTN） group according to whether he or she had hypertension or not. Left and right Brachial-ankle PWV （BaPWV） were measured by VP-1000 automatic arterial stiffness determinator. Blood chemistry and microalbuminuria were measured. Both PWV and microalbuminuria were compared between two groups. Multiple stepwise regression method was used to analyze PWV and all possible related factors. Results Both PWV and microalbuminuria in HTN group were higher than those in NHTN group （P 〈0.001 ,P 〈 0.05 ）. Multiple stepwise regression analysis demonstrated that age, systolic blood pressure,hypertension and microalbuminuria were correlated with PWV independently. Conclusion Age, microalbuminuria, systolic blood pressure and hypertension are independent influentid factors of PWV.
出处
《中国临床保健杂志》
CAS
2009年第3期230-232,共3页
Chinese Journal of Clinical Healthcare
关键词
高血压
脉搏
动脉硬化
白蛋白尿
Hypertension
Pulse
Arteriosclerosis
Albuminuria
