期刊文献+

广西农村部分地区癫及丙戊酸钠疗效的初步调查 被引量:3

An initial investigation of epilepsy and the efficacy of valproate sodium in the treatment of epilepsy in rural areas of Guangxi Zhuang autonomous region
暂未订购
导出
摘要 目的了解广西农村部分地区癫的发病情况、治疗缺口以及丙戊酸钠的疗效。方法利用统一的调查表对广西田东、田阳、平果、天等县已确定或怀疑癫的患者进行调查,再经神经科医生复查后确诊,并对适合使用丙戊酸钠的病例进行疗效观察。结果共诊断癫患者303例,未经治疗46.2%,西药治疗45.5%,仅中药、偏方治疗6.3%,治疗不详2.0%,其中活动性癫人数295例,治疗缺口达81.0%。295例患者进入丙戊酸钠治疗的随访研究,显效率为58.6%,总有效率为75.2%。结论广西农村地区癫的治疗缺口较全国其他农村地区高,经丙戊酸钠治疗后,约75%患者发作可得到有效控制,但是不正规治疗可影响患者的预后,故应重视癫患者的正规治疗。 Objective To study the general state, treatment gap, and the curative effect of valproate sodium of epilepsy in rural areas of Guangxi Zhuang autonomous region. Methods The survey was carried out in the rural areas in Tiandong, Tianyang, Pingguo, Tiandeng, Guangxi Zhuang autonomous region. All patients with a definite or possible epilepsy found during the screening phase were checked again by neurologists. The epileptic thus screened underwent treatment of valproate sodium (VPA). Results Three hundred and three cases of epilepsy were diagnosed, 295 patients were diagnosed as active epilepsy. 46.6% patients didn't take any treatment, 45.5% patients were taking or had taken westen medicine, 6.3% patients treated by Chinese crude drug or local folk prescription, 2% patients were unknown. The treatment gap of active Epilepsy was 81.0%. Two hundred and ninty-five patients entered the treatment group. The significant effective rate of VPA was 58. 6%, the total effective rate of VPA was 75.2%. Conclusion The treatment gap in Guangxi Zhuang autonomous region is higher than domestic other rural areas. About 75% patients with epilepsy were under control by taking VPA, but unregular treatment may result bad prognosis. So it is necessary to think high of regular treatment.
出处 《中国实用神经疾病杂志》 2009年第13期1-3,共3页 Chinese Journal of Practical Nervous Diseases
关键词 癫 治疗缺口 丙戊酸钠 预后 Epilepsy Treatment gap Valproate sodium Prognosis
  • 相关文献

参考文献11

二级参考文献40

  • 1张桁忠,袁成林,李作汉,李晓波,许俊,刘筱洁,赵薛旭,王文志,吴建中.扬州市头桥农村地区的癫癎流行病学调查[J].临床神经病学杂志,2005,18(1):57-58. 被引量:10
  • 2王文志,李世绰,程学铭,戴秀英,孔凡元,宋家仁,闫润民,李昆屯.WHO“癫痫社会控制”方案的扩展性试验研究[J].中国神经精神疾病杂志,1993,19(1):16-19. 被引量:17
  • 3徐敏,蔡秀英,方琪.成年癫痫患者生活质量及其影响因素[J].中国心理卫生杂志,2006,20(6):384-384. 被引量:6
  • 4李世绰.中国六城市居民癫痫的流行病学调查[J].中华神经精神科杂志,1986,19(4):193-193.
  • 5瞿治平.国际癫痫与癫痫综合征分类草案简介[J].中华神经精神科杂志,1986,19(6):375-375.
  • 6薛金堂 杨金晟 等.西北三省十五万人口癫痫发病情况调查[J].中华流行病学杂志,1987,8:165-166.
  • 7朱镛连 吴建中 彭淑敏 等.抗癫痫药物的单药或联合用药问题[J].中华神经精神科杂志,1986,19(6):204-207.
  • 8Kale R. The treatment gap[J].Epilepsia,2002,43:31-33
  • 9Reynolds EH. The ILAE/IBE/WHO epilepsy global campaign history[J]. Epilepsia,2002,43:9-11
  • 10Reynolds EH. Introduction:epilepsy in the world[J].Epilepsia,2002,43:1-3

共引文献317

同被引文献40

  • 1张桁忠,袁成林,李作汉,李晓波,许俊,刘筱洁,赵薛旭,王文志,吴建中.扬州市头桥农村地区的癫癎流行病学调查[J].临床神经病学杂志,2005,18(1):57-58. 被引量:10
  • 2王文志,吴建中,戴秀英,王太平,杨斌,马广玉,袁成林,洪震,赵东海.应用苯巴比妥治疗中国农村地区2455例癫癎患者效果评估[J].中华医学杂志,2006,86(19):1297-1300. 被引量:15
  • 3Mattson RH, Cramer JA. Epilepsy, sex hormones, and antiep- ileptic drugs[J]. Epilepsia, 1985, 26(Suppl 1):40.
  • 4Everitt B J, Keverne EB. Reproduction. In:Lightman SL, Ever- itt B J, editors. Neuroendocrinology. Boston (MA): Blackwell Scientific; 1986. p. 472-537.
  • 5Isojirvi JIT, Laatikainen TJ, Pakarinen A J, et al. Polycystic ovaries and hyperandrogenism in women taking valproate for epilepsy[J]. N Engl J Med 1993, 329(19):1383-1388.
  • 6Isojirvi JI, Repo M, Pakarinen A J, eta/. Carbamazepine, phenytoin, sex hormones and sexual function in men with ep- ilepsy[J]. Epilepsia, 1995, 36(4):366-370.
  • 7Isojirvi JIT, Pakarinen A J, Ylipalosaari PJ, et al. Serum hor- mones in male epileptic patients receiving anticonvulsant medication[J]. Arch Neurol, 1990, 47(16):670-676.
  • 8Duncan S, Blacklaw J, Beastall GH, et al. Antiepileptic drug therapy and sexual function in men with epilepsy[J]. Epilep- sia, 1999, 40(2): 197-204.
  • 9Labrie F, Belanger A, Cusan L, et al. Marked decline in se- rum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging[J]. J Clin Endocrinol Metab, 1997, 82(8):2396-2402.
  • 10Herzog AG, Coleman AE, Jacobs AR, et al. Interictal EEG discharges, reproductive hormones and menstrual disorders in epilepsy[J]. Ann Neurol, 2003, 54(5):625-637.

引证文献3

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部