摘要
目的初步调查西藏农村地区惊厥性癫癎患病率、治疗缺口及患者生活质量。方法利用统一的调查表,对西藏拉萨市墨竹工卡县工卡镇和扎西岗乡、昌都地区芒康县曲孜卡乡进行整群逐户问卷调查。结果共调查14 822人,确诊惊厥性癫癎患者37例,患病率0.25%,其中活动性癫癎患者35例(94.59%),患病率为0.24%。调查前1周内接受西药正规治疗者1例,治疗缺口为97.1%。癫癎患者生活质量评定量表-31(QOLIE-31)总评分平均为(42.15±17.63)分,其中各分项得分中发作担忧得分最低[(22.59±20.31)分]、药物影响的评分最高[(85.83±18.59)分]。年龄、职业、文化程度、经济状况、起病年龄、发作次数为 QOLIE-31低评分的影响因素(P<0.05)。结论西藏农村地区惊厥性癫癎患病率为0.25%,西药治疗缺口大,主要以藏医藏药治疗为主,对西药治疗癫癎的了解很少,生活质量评分低。探索藏西医结合防治癫癎、提高当地医护人员的癫癎防治知识及公众的健康意识迫在眉睫。
Objective To find out the prevalence rate of epilepsy, its treatment gap and quality of life of epilepsy patients in rural areas of Tibet Autonomous Region （TAR）. Methods Cluster sampling was adopted to conduct a door-to-door epidemiological survey among 14 822 rural population in Gongka town, Zhaxigang and Quzika village located in Medrogongka and Markham counties of TAR. The quality of life was measured by the 31-item quality of life in epilepsy inventory （ QOLIE-31 ）. Results Thirty-seven epilepsy patients were diagnosed as convulsive epileptic patients, and the prevalence was 0. 25%. Thirty-five patients （94. 59% ） were diagnosed as active epilepsy, with a prevalence rate of 0. 24%. Only one patient took standard Western Medicine within a week before the survey, and the treatment gap of the active epilepsy was 97.1%. The average QOLIE-31 total score was 42. 15 ± 17.63, and the lowest subcomponent score was 22. 59 ±20. 31 for seizure worry with the highest subcomponent score 85. 83 ± 18.59 for medication effects. Age, occupation, education, economic status, age at epilepsy onset and seizure frequency were significantly correlated with low QOLIE-31 scores （ P 〈 0. 05 ）. Conclusions The prevalence rate and the percentage of untreated patients are lower than that previously reported in other regions, but there is still a greater treatment gap. Most patients receive Tibetan medicine with little or no knowledge about western medicine and their quality of life is poor. It is urgent to provide local medical staff with training on treatment and prevention of epilepsy, and to heighten public health education.
出处
《中华神经科杂志》
CAS
CSCD
北大核心
2007年第9期580-583,共4页
Chinese Journal of Neurology
