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Lugol液染色对食管早期癌和癌前病变的诊断价值

Diagnostic value of Lugol staining for detecting early esophageal cancer and precancerous lesions
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摘要 目的探讨Lugol液染色对食管早期癌和癌前病变的诊断价值。方法对45例食管黏膜可疑病变经内镜以2%Lugol液喷洒染色,观察黏膜染色情况,并取活检送病理组织学检查。结果45例食管病变染色后,39例呈浅染色或不染色,其中食管癌8例(食管早期癌5例,进展期癌3例),Barrett食管5例,轻至中度不典型增生11例。本组Lugol液染色对食管早期癌和癌前病变的检出率达46.7%。结论内镜下应用Lugol液染色结合活检有助于食管早期癌和癌前病变的诊断,且操作简便,具有重要的临床价值。 Objective To study the role of Lugol staining for detecting early esophageal cancer and precancerous lesions. Methods 2 % Lugol solution was adopted to stain esophageal mucosa in 45 cases with esophageal suspicious lesions,observed and multiple biopsies were taken for pathological study. Results Thirty - nine cases were light or non - stained among the 45 cases with Lugol staining . Which revealed 8 esophageal cancers (5 early cancer, 3 advanced cancer), 5 Barrett esophagus, 11 mild - moderate dysplasias. The rate of detecting early esophageal cancer and precancerous lesions with Lugol staining was 46.7 %. Conclusion Lugol staining is helpful for diagnosis of early esophageal cancer and precancerous lesions, and it is simple in operating. The role of Lugol staining in detecting early esophageal cancer and precancerous lesions has important clinical value.
出处 《中国医师进修杂志(内科版)》 2006年第5期33-34,共2页 Chinese Journal of Postgraduates of Medicine
关键词 Lugol液 染色 食管早期癌 癌前病变 Lugol solution Staining Early esophageal cancer Precancerous lesions
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参考文献3

  • 1张军,龚均,罗金燕,邓登豪,佐爱丽.卢戈氏染色诊断食管早期癌和表浅癌价值的评价[J].中华消化内镜杂志,1998,15(3):142-144. 被引量:51
  • 2Gruppo Operativo perio studio delle precaneerosi dell ,esofago, Barrett's esophagus:epide miologieal and clinical results of s muticentric survey. In J Cancer, 1991,48 : 364 - 368.
  • 3Guanrei Y,He H,Sung Liang Q ,et al. Endoscopic diagnosis of 115 cases of early esophageal carcinoma. Endoscopy, 1982,14: 157.

二级参考文献4

  • 1Nothmann,E.J.,Wright J.R.,Schuster,M.M.In vivo vltal staining as an aid to identification of esophageal and gastric mucosal juntion in man. Digest. Dis.,1972,17:919.
  • 2Akaska,Y,Okuda,S.,Ida,K.Basic Research and clinical application in esophagoscopic Lugol's staining. Gastroenterol,Endose.,1974,18-84.
  • 3Ide H.,Endo M.Intramural metastasis and multiple lesions in esophgeal cancer. In"Geka Mook 24"ed.by M.Endo.Kanehara Co.Tokyo,1982,128.
  • 4Guanrei Y,He H,Sungliang Q,et al. Eneoscopic diagnosis of 115 cases of early esophageal carcinoma. Endoscopy,1982,14:157.

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