摘要
目的：探讨蜂胶黄酮对小鼠免疫功能的影响。方法：分别以175、350、700 mg/kg BW剂量的总黄酮（以芦丁计）给小鼠连续灌胃30-35 d后,检测各项免疫指标。结果：蜂胶黄酮能明显刺激小鼠的脾淋巴细胞增值、转化作用,促进小鼠迟发型变态反应作用,提高小鼠抗体生成细胞数和血清溶血素水平,促进小鼠单核-巨噬细胞碳廓清作用,增强小鼠的单核-腹腔巨噬细胞吞噬能力,提高小鼠NK细胞活性。结论：提示蜂胶黄酮具有增强免疫功能的作用。
Objective：To explore the effect of total flavones in propolis on enhancement of mice＇s immune function. Methods： Total flavones in propolis were consecutively orally given to mice with the doses of 175,350 and 700 mg/kg of body weight for 30 -35 days and then various immune indexes were determined. Results：Total flavones in propolis was capable of stimulating multiplication and transformation of mice＇s spleen lymphocytes, promoting delayed hypersensitivity, increasing the quantity of antibody - producing cells, enhancing the level of serum hemolysin, promoting the expurgation effect and the phagocytic function of monocyte/macrophage and increasing the activity of natural killer. Conclusion：It is suggested that total flavones in propolis could enhance mice＇s immune function.
出处
《中国卫生检验杂志》
CAS
2009年第7期1658-1660,共3页
Chinese Journal of Health Laboratory Technology
关键词
蜂胶黄酮
免疫功能
小鼠
Total flavones in propolis
Immune functions
Mice
